Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Promotores: W. Jiskoot, F. Ossendorp

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Promotor: Prof.dr. M. Ubbink

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Promotor: Prof.dr. J. Kuiper

Op 17 december 2018 verdedigde Dejian Kong zijn proefschrift 'Civil Liability for Damage caused by Global Navigation Satellite System'. Het promotieonderzoek is begeleid door promotor prof. dr. P.M.J. Mendes de Leon.

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

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This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.

How do nanoparticles bioaccumulate and biodistribute in organisms?

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

Hoogleraar Kansrekening Frank den Hollander ontvangt een NWO-TOP-subsidie van 470 duizend euro. Twee promovendi gaan hiermee een recent ontwikkelde wiskundige theorie, waarmee macroscopische eigenschappen van systemen van microscopisch kleine deeltjes te voorspellen zijn, verder uitbreiden.

Promotor: S.M. Verduyn Lunel

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Lezing, seminar

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Wat is 'Interaction between Legal Systems' (ILS) en wat betekent het als profileringsgebied binnen de Faculteit der Rechtsgeleerdheid? Hier meer over op de startbijeenkomst van ILS 2.0 op 26 oktober 15.00 – 17.00 in de Grotiuszaal (A051 KOG). De middag wordt afgesloten met een borrel in de Global Lo…

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

Promotor: Prof.dr. C.W.J. Beenakker

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

Promotie

The space between the stars isn't simply a void; it also contains substances such as methanol and carbon dioxide. So far, chemical theories have been unable to explain how these substances originate under circumstances that should make it impossible. Fedor Goumans has been awarded a Veni subsidy to…

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

In de afgelopen drie decennia is er een sterke toename van het aantal denktanks in de meeste westerse democratieën, waarbij zij steeds meer gezien worden als belangrijke spelers in beleidsprocessen. Toch blijft hun precieze bijdrage aan beleidsvorming gecontesteerd.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…