59 zoekresultaten voor “innate immunity” in de Publieke website
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
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Systems vaccinology: molecular signatures of immunity to Bordetella pertussis
Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Computational modeling of mycobacterium infection and innate immune reponse in zebrafish
Promotor: Prof.dr. J.N. Kok
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ERC-funded Postdoctoral Researcher in Molecular Plant Immunity
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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ERC-funded PhD candidate in Molecular Plant Immunity
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Control of Western flower thrips through jasmonate-triggered plant immunity
We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.
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Bart Roep
Faculteit Geneeskunde
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Customary International Criminal Law and Head of State Immunity by Judge Chile Eboe-Osuji
On 12 September 2019, Judge Chile Eboe-Osuji, President of the International Criminal Court (ICC), delivered a lecture on Customary International Criminal Law and Head of State Immunity to open the academic year for the Advanced LL.M. Programmes in Public International Law & International Dispute Settlement…
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Cornelis Hokke
Faculteit Geneeskunde
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Mast cell-mediated immune modulation in experimental Rheumatoid Arthritis and Atherosclerosis
In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.
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Cornelis van Kooten
Faculteit Geneeskunde
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Frank Baas
Faculteit Geneeskunde
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Surviving embryogenesis: The extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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Heterologous Immunity in Organ Transplantation
Promotie
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Novel mediators of anti-tumor immunity
Promotie
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Characterization of innate immune cells in the glioma microenvironment
Promotie
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Airway epithelial innate host defence in chronic obstructive pulmonary disease
Promotie
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The Function of Toll-like receptor 2 in Infection and Inflammation
Promotie
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Cytokine-mediated regulation of immunity during persistent viral infection
Promotie
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T and NK cell immunity after hematopoietic stem cell transplantation
Promotie
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Natural and Vaccine derived immunity against the human papillomavirus
Promotie
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The Role of the innate and adaptive immune system in Vascular remodelling
Promotie
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Dubbelslag tegen ontstekingsziekten
Combinatie van twee potentiële geneesmiddelen geeft zicht op een 'superblokkade' van een overactief immuunsysteem, schrijven Leidse wetenschappers in Nature. De doorbraak was het kristalliseren van het betrokken membraaneiwit.
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Shaping innate immune responses: mechanisms that control type I interferon production
Promotie
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resistance of Human papillomavirus- infected or -transformed cells to Th1 immunity
Promotie
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Outcome after Paediatric Stem Cell Transplantation for Inborn Errors of Immunity
Promotie
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Control of Western flower thrips through jasmonate-triggered plant immunity
Promotie
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Witte bloedcellen in transparante embryo’s
Leidse moleculair-celbiologen in de onderzoeksgroep van Annemarie Meijer hebben nieuwe genen ontdekt die specifiek tot expressie komen tijdens de vroege ontwikkeling van macrofagen in de zebravis, waaronder een signaaleiwit dat essentieel is voor de migratie van macrofagen tijdens de immuunreactie op…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Green defense against thrips- Exploring natural products for early management of western flower thrips
As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).
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Novel formulations and delivery strategies for inactivated polio vaccines : new routes with benefits
This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.
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Genetic manipulation and genetic-based dissection of tumor-specific immunity
Promotie
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The impact of defense hormones on the interaction between plants and the soil microbial community
The soil ecosystem consists of the largest reservoir of biodiversity on Earth.
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cell-intrinsic mechanisms that dictate systemic inflammation and anti-tumor immunity
Promotie
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Studieprogramma
Bij Biomedische Wetenschappen word je opgeleid tot wetenschapper in het biomedisch veld. Wat houdt dat eigenlijk precies in en wat leer je allemaal in de bachelorfase?
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Nieuw inzicht in gedrag immuuncellen biedt kansen voor kankerbehandeling
Een internationale groep wetenschappers heeft ontdekt dat bepaalde cellen van ons immuunsysteem – de zogenaamde T-cellen – onderling communiceren en als een team samenwerken: om een infectie te bestrijden stimuleren ze elkaars groei, maar tegelijkertijd remmen ze elkaar af wanneer er een overschot aan…
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Immuniteit, Infectie en Tolerantie
Het immuunsysteem beschermt ons tegen ziekten, maar soms gaat het mis. Dan dringt er toch een vijand binnen of valt het immuunsysteem ons eigen lichaam aan, waardoor we ziek worden. Artsen en onderzoekers van het Leids Universitair Medisch Centrum (LUMC) willen het immuunsysteem zodanig sturen, dat…
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Postdoc in the fields of single cell biophysics and biomolecular condensate mechanics
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)