164 zoekresultaten voor “innate immune system” in de Publieke website

• The interplay between lipids and the immune system in atherosclerosis Onderzoeksoutput

  Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

• Modulation of the immune system for treatment of atherosclerosis Onderzoeksoutput

  Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

• From immune suppression to immune modulation in type 1 diabetes patients Agenda - 5 oktober 2021

  Promotie

• Insights from modeling metabolism and amoeboid cell motility in the immune system Onderzoeksoutput

  This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

• Novel Immune Cell-Based Therapies for Atherosclerosis Onderzoeksoutput

  Promotor: Prof.dr. J. Kuiper

• Toll-like receptor signaling in the innate immune system of zebrafish larvae Agenda - 20 december 2016

  Promotie

• Wiles and Wanderings: Immune-evasive maneuvers of skin-penetrating parasites Agenda - 5 oktober 2021

  Promotie

• 
  Noortje Dannenberg Promovendus

  Wiskunde en Natuurwetenschappen

• Intradermal delivery of nanoparticulate vaccines using coated and hollow microneedles Onderzoeksoutput

  In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.

• Clinical implications of immune cell infiltration in vulvar intraepithelial neoplasia Agenda - 1 december 2015

  Promotie

• Modelling the role of cytotoxic T lymphocytes in tumour regression Onderzoeksoutput

  Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

• Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis Onderzoeksoutput

  Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

• B cell modulation in atherosclerosis Onderzoeksoutput

  Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

• Hierarchical Systems Onderzoeksoutput

  The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.

• Wrapping up: nidovirus membrane structures and innate immunity Agenda - 28 november 2017

  Promotie

• Airway epithelial innate host defence in chronic obstructive pulmonary disease Agenda - 11 oktober 2018

  Promotie

• Therapeutic targeting of immune-escaped cancers Agenda - 18 februari 2020

  Promotie

• Tolerance and Immune Regulation in Rheumatoid Arthritis Agenda - 1 oktober 2019

  Promotie

• Immune-based therapies in ovarian cancer Agenda - 13 juni 2017

  Promotie

• Functional aspects of the adaptive immune system in arthritis Agenda - 8 maart 2017

  Promotie

• Modulation of leukocyte homeostasis in atherosclerosis Onderzoeksoutput

  Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

• Cholesterol metabolism and hematopoiesis interaction in atherothrombosis Onderzoeksoutput

  Cardiovascular disease is the leading cause of death worldwide.

• Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance Onderzoeksoutput

  Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

• Pharmaceutical Aspects of Subvisible Particles in Protein Formulations Onderzoeksoutput

  Promotor: W. Jiskoot, Co-promotor: A. Hawe

• Analysis of Energy Systems Onderzoeksproject

  The Institute of Environmental Sciences has carried out and participates in several projects that deal with the analysis of energy systems.

• Immune cell complexity in the tumor microenvironment of breast cancer Agenda - 22 oktober 2019

  Promotie

• Mechanisms of immune evasion in Epstein-Barr virus infection Agenda - 8 september 2016

  Promotie

• Targeting the adenosinergic system Onderzoeksoutput

  Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

• Insights from modeling metabolism and amoeboid cell motility in the immune system Agenda - 15 juli 2021

  Promotie

• Advanced Computing and Systems (MSc)

• System Biomedicine and Pharmacology (MSc)

  Deze opleiding is gericht op de ontwikkeling van computermodellen die de werking van medicijnen voorspellen, het individualiseren van bestaande behandeltherapieën en het ontwikkelen van innovatieve, analytische tools voor het personaliseren van de gezondheidszorg.

• PostDoc Therapeutic Immunomodulation Vacature

  Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

• In vivo modelling of Ewing sarcoma in zebrafish Onderzoeksoutput

  Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska

• Pulses in singularly perturbed reaction-diffusion systems Onderzoeksoutput

  Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer

• Development of the human fetal immune system: Novel insights from high-dimensional single-cell technologies Agenda - 8 oktober 2019

  Promotie

• PostDoc: Balanced Lethal System Genomics Vacature

  Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)

• High-dimensional profiling of immunotherapy responsive immune cells in cancer Agenda - 8 juni 2021

  Promotie

• Regulation of DNA damage and immune response pathways by post-translational protein modification Agenda - 9 september 2020

  Promotie

• Mining Sensor Data from Complex Systems Onderzoeksoutput

  Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

• Mast cell mediated immune modulation in experimental Rheumatoid Arthritis and atherosclerosis Agenda - 29 september 2016

  Promotie

• Immune regulation by CD4+CD49b+ T cells & B cell responses in arthritis Agenda - 29 november 2016

  Promotie

• Immune parameters affecting maternal tolerance towards the fetus in normal and aberrant pregnancies Agenda - 16 juni 2020

  Promotie

• PI3K signaling and adherens junctions in invasive lobular breast cancer Onderzoeksoutput

  Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

• Precision modeling of breast cancer in the CRISPR era Onderzoeksoutput

  The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

• Liposome-based synthetic long peptide vaccines for cancer immunotherapy Onderzoeksoutput

  Promotores: Wim Jiskoot; Ferry Ossendorp

• Anisotropy, multivalency and flexibility-induced effects in colloidal systems Onderzoeksoutput

  We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.

• Fuzzy systems and unsupervised computing: exploration of applications in biology Onderzoeksoutput

  In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

• Regeneration and Replacement of Beta-cells and Aspects of Immune-intervention in Type 1 Diabetes Agenda - 19 mei 2016

  Promotie

• The effect of parasitic co-infections on immune responses in Gabon: Particular emphasis on malaria and helminths Agenda - 7 juli 2016

  Promotie

• Onderzoeksoutput