35 zoekresultaten voor “inflammation” in de Publieke website
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Chemokine signaling mechanisms underlying inflammation and infection control: insights from the zebrafish model
This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.
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arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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TechTalk Autoimmunity & Inflammation
Lezing
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Nanomaterial safety for microbially-colonized hosts: Microbiota-mediated physisorption interactions and particle-specific toxicity
The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.
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Human skin equivalents for atopic dermatitis: investigating the role of filaggrin in the skin barrier
Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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The role of inflammation in sciatica
Promotie
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Regulation of Inflammation in Uveal Melanoma
Promotie
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Investigations on the role of impaired lysosomes of macrophages in disease
The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.
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Endothelial dysfunction and inflammation in diabetic nephropathy
Promotie
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
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Inflammation as a target for treatment in hand osteoarthritis
Promotie
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The role of inflammation in cardiac and vascular remodelling
Promotie
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Coagulopathy and blood abnormalities in cancer and inflammation
Promotie
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Ocular inflammation in age-related eye diseases
Promotie
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Chemokine signaling mechanisms underlying inflammation and infection control: insights from the zebrafish model
Promotie
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Investigation of skin inflammation with a novel dermatology toolbox for early phase clinical drug development
Promotie
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arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Promotie
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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The Function of Toll-like receptor 2 in Infection and Inflammation
Promotie
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Computer-aided techniques for assessment of MRI-detected inflammation for early identification of inflammatory arthritis
Promotie
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Control: the cancer cell-intrinsic mechanisms that dictate systemic inflammation and anti-tumor immunity
Promotie
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Jantine Brussee tweede in PhD-competitie
Farmacologe Jantine Brussee won op 4 oktober de tweede prijs in de Figon-Pfizer PHD Student competition tijdens de DUtch Medicine Days in Ede.
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Staff position (Assistant, Associate, Full Professor) in drug development for inflammatory diseases (fulltime)
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Biological evaluations of nanocarriers to improve the effectiveness of colorectal cancer treatment
Promotie