In welke mate zijn beoordelingen op basis van een videodossier betrouwbaar, generaliseerbaar en valide?

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: J. A. Bouwstra

Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

Promotor: Prof.dr. T. Hankemeier

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Wiskunde en Natuurwetenschappen, Sterrewacht Leiden (STRW)

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

Promotor: J.S. Kaastra Co-promotor: E. Constantini

A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.

Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.

Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets

Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)

Promotor: Prof.dr. R.M.H. Merks

De huidige en toekomstige quantumcomputers vormen dezelfde uitdaging als de laser in zijn begindagen. In theorie werd voorspeld dat de laser een bron van zeer speciaal, zeer krachtig licht zou zijn. Maar in die tijd waren er geen duidelijke toepassingen voor. Critici van het idee noemden het een probleem…

The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

Promotor: Prof.dr. G.P. van Wezel

Promotor: B. van de Water

Promotor: I. Snellen, Co-Promotor: M. Kenworthy

Speeddates met studentes Natuurkunde en vrouwelijke (technisch) natuurkundigen uit het bedrijfsleven, een college volgen van natuurkundige prof.dr. Doris Heinrich, zelf onderzoek doen en een High Tea. Daarvoor kwamen zo'n 90 meisjes naar de Physics Ladies's Day op 31 oktober.

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

The idea of citizens and public professionals collaborating to provide public services has widely spread in several countries around the globe. Co-production is often presented as the go-to solution for challenges like a legitimacy crisis of both the government and the market, and financial concerns.…

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.

Governance and Global Affairs

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

This thesis contributes to studying primordial cosmology theories and their detectability in future observations.

Promotie

Promotor: A.P.IJzerman Co-promotor: A. Bender

Promotor: Prof.dr. B.R. Katzy, Prof.dr. J. de Vries

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Promotor: Prof.dr. J.W.M. Frenken

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

HIIT staat voor High Intensity Interval Training, een term die we de laatste tijd steeds vaker in de fitness tegenkomen. High Intensity Interval Training of HIIT, is een circuit gebaseerde high energy mix van cardio- en krachtoefeningen. Wetenschappelijk is bewezen dat dit een van de meest effectieve…

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

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The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

In unconventional high temperature superconductors, supercurrent vortices are known to spoil the Landau levels. In this thesis the emergence of Landau levels is studied in different types of superconductors: Weyl superconductors, and the Fu-Kane heterostructure.

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.