Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

Promotor: S.M. Verduyn Lunel

Op 9 september 2009 viert de opleiding Life Science and Technology (LS&T) haar tienjarig bestaan.

CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…

Sander van Lidt de Jeude studeert in Leiden Natuurkunde en volgde de minor Geneeskunde van Medical Delta: ‘Ik wilde graag iets toegepasts doen.’

How can prospective LCA be streamlined in a way that its practical application in research and technology development increases?

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

Promotores: G. Persoon, R. Schefold

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Hoe kan de methode om de gecombineerde effecten van metaal-gebaseerde chemische stoffetn te bepalen worden verbeterd?

Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.

What is movements and corridors of the Bornean pygmy elephant in Sebuku forest? What is the nature of human-elephant conflict in Nunukan District in time and space? What are the diets of the Bornean elephants related to crop raiding?

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

Migration imposes special pressures on the meaning, experience and organization of lifecycle rituals. These pressures are felt most strongly by Muslim migrants to Western Europe. In this innovative study, Nathal M. Dessing examines the effects of migration on the life cycle rituals of Moroccan, Turkish…

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

Freshwater and brackish water ecosystems are arguably the most vulnerable ecosystems on earth, due to concentrated human developments in and around them. The Pontocaspian (PC) region located at the border of Europe and Asia contains a variety of brackish water ecosystems and unique inhabitants, known…

De startende en jonge bedrijven in het Bio Science Park zijn in 2010, net als in 2009, tegen de crisistrend in opnieuw gegroeid. De groei betreft omzet, aantal medewerkers en gehuurde vierkante meters.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…

Lezing

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

De cel is een zakje met water, en daarin opgelost spelen zich de levensprocessen af. Dat weet iedere bioloog, maar het klopt niet, vermoedt prof.dr. Rob Verpoorte: naast water lijken voorheen onbekende natuurlijke oplosmiddelen ook een rol te spelen. Dat zou de droogte- en koudebestendigheid van planten…

Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.

Dichtslibbende bloedvaten zijn een belangrijke oorzaak voor hart- en vaatziekten. Een te hoog cholesterolgehalte speelt hierbij een rol. Biofarmaceut Illiana Meurs heeft nieuwe inzichten verkregen in mechanismen die cholesterol uit het lichaam kunnen verwijderen. Ze promoveert 7 juni.

Governance and Global Affairs

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

Promotie

Op 2 en 3 oktober 2017 heeft een delegatie van de Afdeling Jeugdrecht deelgenomen aan de 15e Europese regionale conferentie van de International Society for the Prevention of Child Abuse and Neglect in Den Haag.

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

De opleiding Life Science and Technology (LST) stond 9 september 2014 met een feestelijk gebakje stil bij haar 15 jarig bestaan. Het gaat bijzonder goed met de opleiding. Er zijn veel eerstejaars studenten en LST masterstudenten vinden of vóór hun diploma-uitreiking of er vlak na een goede baan.

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet