This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

This thesis has three main parts. The first part gives an algorithm to compute Hilbert modular polynomials for ordinary abelian varieties with maximal real multiplication. Hilbert modular polynomials of a given level b give a way of finding all of the abelian varieties that are b-isogeneous to any given…

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

Promotor: A. Achúcarro Co-promotor: A. Boyarsky

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Promotor: Prof.dr. M. Ubbink

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

What are interactive effects of human pressures on aquatic communities?

Promotor: Prof.dr. A.W. van der Vaart

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

Promotor: M.L. van Hecke

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

To study how planetary systems come into existence we study much younger systems still in formation.

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Promotor: A.P. IJzerman

Promotor: A.P. IJzerman

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Promotores: T.H. Oosterkamp, N. de Jonge

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

Promotores: S.F. Portegies Zwart, E. M. Rossi

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Promotor: Prof.dr. T. Schmidt

Lezing

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

De Leidse psycholoog Rebecca Schaefer laat zien dat wanneer muziek ingezet wordt bij het aanleren van een nieuwe beweging, de verbindingen in de hersenen toenemen tussen de gebieden in het brein die belangrijk zijn voor gehoor en beweging. Bij het aanleren van dezelfde beweging zonder muziek was deze…

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

My work focuses on a class of astronomical objects called protoplanetary disks.

This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.

Promotor: Prof.dr. B. van de Water

Promotor: I. A. G. Snellen, Co-promotor: M. A. Kenworthy

Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…

Promotor: Prof.dr. A. Achucarro

Promotor: Prof.dr. H.A.G. Wijshoff

To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Promotor: F. Arbab

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Promotor: V. Vitelli, Co-promotor: J. Paulose