How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

Promotor: E.F. Smets, Co-promotor: J. Geml

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Promotor: E.F. Smets Co-promotor: J. Geml

What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Promotor: Prof.dr. G.P. van Wezel

De afdeling Environmental Biology (CML-EB) houdt zich bezig met vraagstukken rondom biodiversiteit en natuurlijke hulpbronnen op het platteland in westerse en niet-westerse gebieden.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Prof.dr. J. Memelink

Lees hier alles over de verschillende projecten van de Young Academy Leiden.

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

In 2019 bestond de Universiteit Leiden 444 jaar. Deze bijzondere leeftijd vroeg om een bijzondere viering, samen met de inwoners van Leiden en Den Haag. In, met en voor de stad.

De Young Academy Leiden (YAL) is een selecte groep jonge academici aan de Universiteit Leiden. De YAL, opgericht in begin 2019, dient als platform om enthousiaste en ambitieuze jonge academici (post-PhD), die aan het begin van hun carrière staan, bij elkaar te brengen. YAL-leden vertegenwoordigen…

Promotie

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.

Promotie

Promotie

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

Promotor: Prof.dr. M.T.M. Koper, Co-Promotor: F. Calle-Vallejo

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Promotores: G.W. Canters, T.J. Aartsma

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

Course program 2021-2022

De YAL stimuleert interdisciplinaire samenwerking.

Studievoorlichting, Online Experience

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska