34 zoekresultaten voor “formulation” in de Publieke website
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Formulation of influenza T cell peptides: In search of a universal influenza vaccine
Promotores: Prof.dr. G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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dioxide spray drying for the production of stable dried protein formulations
Promotor: W. Jiskoot, Co-promotor: H.A. Every
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Novel formulations and delivery strategies for inactivated polio vaccines : new routes with benefits
This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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PLGA-based particulate vaccine delivery systems for immunotherapy of cancer
Promotores: W. Jiskoot, F. Ossendorp
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Formulation of Peptide-Based Cancer Vaccines
Promotie
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A novel formulation for skin barrier Repair
Promotie
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Dyslipidemia at the crossroad of the skin barrier and the arterial wall
The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…
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Novel formulations and delivery strategies for inactivated poliovirus vaccines
Promotie
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Adjuvanted nanoparticulate seasonal influenza vaccines
Promotor: W. Jiskoot, Co-promotor: A. Kros
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Statistical modelling of time-varying covariates for survival data
This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.
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Substances from Cradle to Grave
Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…
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Towards a mechanistic understanding of nanoparticle behavior using zebrafish
The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.
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Algorithms for finite rings
Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Hydrodynamics and the quantum butterfly effect in Black Holes and large N quantum field theories
Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?
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CONSENT
CONSENT (Consumer sentiment regarding privacy on user generated content services in the digital economy) is a research project funded by the European Union under the 7th Framework Programme. The question central to this research is whether recent changes to consumer and commercial practices developed…
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De jacht op nanoplastics
Hoe gevaarlijk zijn micro- en nanoplastics? Hebben ze invloed op het milieu? Zijn ze schadelijk voor ons lichaam? Deze vragen kunnen we dankzij Fazel Abdolahpur Monikh eindelijk gaan beantwoorden. Samen met zijn collega’s ontwikkelde hij een methode om plasticdeeltjes van nanoformaat te detecteren en…
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Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
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Farmaceutisch Wereldcongres: interview congresvoorzitter Meindert Danhof
In mei 2017 zal het driejaarlijkse FIP Pharmaceutical Sciences World Congress (PSWC) worden gehouden in Stockholm. We hadden een interview met de congresvoorzitter: Professor dr. Meindert Danhof van het LACDR, Universiteit Leiden.
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This Week's Discoveries | 22 oktober 2019
Lezing
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This Week's Discoveries | 12 May 2020
Lezing
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Statistical modelling of time-varying covariates for survival data
Promotie
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The Anthropomorphic Hegemony of Subjectivity: Critical Reflections on Law and the Question of the Animal
Promotie
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Is the WPS Agenda Working? Preventing Conflict Related Sexual Violence and Beyond
Round Table
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Campus The Hague Career Event
Congres/symposium