84 zoekresultaten voor “exposure therapy” in de Publieke website
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Marike KooistraFaculteit der Sociale Wetenschappen
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Rational empiric antibiotic therapy in clinical practice & policy making
Promotie
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
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Metabolomic fingerprint biomarkers to guide antibiotic therapy and reduce resistance development
Ontwikkeling van resistentie tegen antibiotica kan optreden als patiënten onnodig of te lang met antibiotica behandeld worden. Diagnostiek waarmee snel een bacteriële infectie vastgesteld kan worden, of de response op antibiotica bepaald kan worden, zijn daarom belangrijk om therapie te optimaliseren…
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Haico van AttikumFaculteit Geneeskunde
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Exposure and health Assessment of Persistent Organic Pollutants (POPs) at e-waste recycling site among workers in the informal sector in Nigeria
Do e-waste workers display enhanced effects of adverse health effects due to informal e-waste processing in Nigeria? Is there a difference between the health outcomes of the exposed and the control groups? Are there difference in health effects within and between job groups (collectors, dismantlers,…
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Rianne de KleineFaculteit der Sociale Wetenschappen
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The noisy underwater world: the effect of sound on behaviour of captive zebrafish
Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn
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Waarom een dragqueen minder exposure krijgt dan een racist
Technologische ontwikkelingen gaan in een razend tempo, zo ook op het gebied van kunstmatige intelligentie. Voor minderheidsgroepen zoals de LHBT+ gemeenschap kan die ontwikkeling echter gevaarlijk zijn, schrijft onderzoeker Eduard Fosch Villaronga in een ingezonden brief in Nature Machine Intellige…
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Chris HoeboerFaculteit der Sociale Wetenschappen
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Judith BovéeFaculteit Geneeskunde
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Lioe-Fee de Geus-OeiFaculteit Geneeskunde
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The Metallophilic Interaction between Cyclometalated Complexes: Photobiological Applications
In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.
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Pharmacogenomics in Drug Development: Implementation and Application of PKPD Model Based Approaches
Model based approaches, integrating physiological parameters or linking exposure with response, are powerful tools to quantify and evaluate the impact of genetic differences that are reflected as variability of drug exposure and/or clinical response(s). This thesis “Pharmacogenomics in Drug Development: …
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Preparing for CADASIL therapy
Promotie
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TechTalk Cancer Diagnostics & Therapy
Lezing
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Art therapy & Anxiety
Promotie
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Gene therapy and nerve repair
Promotie
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Optimization of UV Exposure Schedules for Tanning
Promotie
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Surgical therapy of organic mitral valve disease
Promotie
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
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Dynamics of TNFalpha signaling and drug-related toxicity
In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.
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Music therapy in Huntington's disease
Promotie
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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Long-term neurodevelopmental outcome after fetal therapy
Promotie
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Mechanisms of melanoma-targeting antibody therapy in mice
Promotie
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Aortic Valve Disease: Novel Imaging Insights from Diagnosis to Therapy
Promotie
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Host-Directed Therapy for Intracellular Bacterial Infections
Promotie
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optimization methods for image registration in adaptive radiation therapy
Promotie
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Therapeutic RNAi-based gene therapy for neurodegenerative disorders
Promotie
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GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.
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Effects of pesticides on aquatic macrofauna in the field
Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver
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Hoe klinkt het Hofplein, nu en in de toekomst?
Hoe ervaren omwonenden en gebruikers het Rotterdamse Hofplein? De uitkomsten en aanbevelingen van het geluidsbelevingsonderzoek staan in het rapport
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Mind the time: 24-hour rhythms in drug exposure and effect
Promotie
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Tailoring adjuvant therapy for hormone receptor-positive early breast cancer
Promotie
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T-Control: T-Cell Therapy in the Context of Allogeneic Stem Cell Transplantation
Promotie
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
Promotie
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Short term fasting, IGF/insulin-axis and therapy outcome in patients with cancer
Promotie
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
Promotie
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Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes
Almost all bacteria are enveloped by a cell wall that provides cellular protection.
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When materials become critical: lessons from the 2010 rare earth crisis
Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn
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The Effects of Breast Cancer Therapy on Estrogen Receptor Signaling Throughout the Body
Promotie