989 zoekresultaten voor “evidence based” in de Publieke website
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Studying the Benefits of Using UML on Software Maintenance: an Evidence-Based Approach.
Including modelling as part of software development appears to have various benefits.
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
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Current challenges in statistical DNA evidence evaluation
Promotor: R.D. Gill, F. Taroni
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Ionica Smeets
Wiskunde en Natuurwetenschappen
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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Pharmacology based toxicity assessment: towards quantitative risk prediction in humans
Promotor: Prof.dr. M. Danhof
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The Rome Statute as Evidence of Customary International Law
Op 9 april 2019 verdedigde Yudan Tan haar proefschrift 'The Rome Statute as Evidence of Customary International Law'. Het promotieonderzoek is begeleid door promotor prof. dr. W.A. Schabas.
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The impact of obesity on the pharmacokinetics of drugs in adolescents and adults
Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst
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Science based business
Science Based Business (SBB) verbindt de domeinen wetenschap, bedrijfsleven en beleid. Wetenschappelijk onderzoek waar we ons in Leiden op richten, bijvoorbeeld op het gebied van kunstmatige intelligentie, belooft onze samenlevingen ten goede te komen. Het vertalen van wetenschap naar positieve maatschappelijke…
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Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design
Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.
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Science based business
Science Based Business (SBB) verbindt de domeinen wetenschap, bedrijfsleven en beleid. Wetenschappelijk onderzoek waar we ons in Leiden op richten, bijvoorbeeld op het gebied van kunstmatige intelligentie, belooft onze samenlevingen ten goede te komen. Het vertalen van wetenschap naar positieve maatschappelijke…
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Bèta-inzicht rukt op in de rechtszaal
Toeval? Verpeegkundige Lucia de B. zou tijdens haar werk dertien mensen – waaronder een aantal baby’s – hebben vermoord: de kans dat deze mensen toevallig tijdens of vlak voor haar dienst spontaan zouden zijn overleden, werd in 2002 door een statisticus zo klein geacht dat er geen sprake kon zijn van…
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Activity-based proteomics of the endocannabinoid system
This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.
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Nanowire based Tandem Solar Cells
In this project innovative technology for photovoltaics cells is developed and analysis of ecological and health related risks are explicitly accounted for.
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Activity-based protein profiling of diacylglycerol lipases
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Fetal and Neonatal Alloimmune Thrombocytopenia evidence based screening
Promotie
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Filter-based reconstruction methods for tomography
Promotor: K.J. Batenburg
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Evidence based evaluation of new techniques in minimally invasive surgery
Promotie
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Activity-based protein profiling of glucosidases, fucosidases and glucuronidases
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea
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Sustaining Ethical Aquatic Trade (SEAT)
Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.
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A versatile tuple-based optimization framework
Promotor: Prof.dr. H.A.G. Wijshoff
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Technisch Applicatiebeheerder Windows based applicaties
ICT Shared Service Centre
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Determines Perceptions of Bias toward the International Criminal Court? Evidence from Kenya
What Determines Perceptions of Bias toward the International Criminal Court? Evidence from Kenya. In dit artikel, gepubliceerd in op de website SAGE Journals in het Journal of Conflict Resolution, onderzoeken de auteurs Geoff Dancy, Yvonne Marie Dutton, Tessa Alleblas, Eamon Aloyo de houding ten opzichte…
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Principles of Evidence in Investor-State Arbitration, Burden, Standards, Presumptions & Inferences
Op 28 februari 2019 verdedigde Kabir Duggal zijn proefschrift 'Principles of Evidence in Investor-State Arbitration, Burden, Standards, Presumptions & Inferences'. Het promotieonderzoek is begeleid door promotor prof. dr. E. De Brabandere.
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Research-based education (Engelstalig)
Didactiek
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Development of life cycle assessment for residue-based bioenergy
Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Rationally designed peptide based functional biomaterials
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Constraint-Based Analysis of Business Process Models
Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.
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gezamenlijke professionalisering op internationale scholen rond inquiry based learning
Met dit project wordt onderzocht hoe docenten op drie internationale scholen zich gezamenlijk professionaliseren rond het thema ‘Inquiry based teaching’. Gegeven de rijkdom aan ervaring en achtergronden van de docenten op internationale scholen, kan worden verwacht dat docenten veel kunnen leren…
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Remote sensing-based assessment of functional diversity for polar ecosystems
1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Development of life cycle assessment for residue-based bioenergy
Wat zijn de belangrijkste thema's in het uitvoeren van systemen voor bio-energie ?
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
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Research
The mission of our group is understanding how science communication works to improve the interaction between science and society.
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Mononuclear spin-transition materials based on the bapbpy scaffold
Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Onderwijs
De programmagroep verzorgt onderwijs op het gebied van diagnostiek, behandeling/preventie/interventie, neuropsychologisch onderzoek, gedragsobservaties, klinische vaardigheden, gesprekstechnieken, ondersteuning van leerkrachten en ouders, kennis over verstandelijke beperkingen en ontwikkelingsstoornissen…
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Corporate venture management in SMEs: evidence from the German IT consulting industry
Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Squaramide-based supramolecular materials for 3D cell culture applications
Promotie
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Cleared for take-off, Game-based learning to prepare airline pilots for critical situations
Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.