The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

Festival

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

Congres/symposium, Book launch

In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).

Promotor: G.P. van Wezel

How can we develop and further improve life cycle impact assessment methods, characterisation factors and normalisation factors?

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

In Europe a number of production and communication strategies have long tried to establish local products as resources for local development. At the foot of the Alps, this scenario appears in all its contradictions, especially in relation to cheese production. The Heritage Arena focuses on the saga…

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

The department of Industrial Ecology is dealing with research into the development of tools for decision making on sustainable production and consumption.

Lezing

Are there significant differences among the environmental impacts resulting form the production of Asian aquaculture commodities and what are the main causes for these?

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Promotor: Prof.dr. M. Ubbink

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

Promotie

The global agri-food system plays a critical role in food security and environmental issues.

Cardiovascular disease is the leading cause of death worldwide.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.

The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…

This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.

Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte

Promotie

Promotie

BioSolar Cells is a five-year research project in which ten knowledge institutions and 45 private industries work together.

Promotie

Promotie

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

Promotor: Prof.dr. G.P. van Wezel

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

Promotores: G.W. Canters, T.J. Aartsma

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.