In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Unfolding potential

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Veel kinderen leren niet op een niveau dat aansluit bij hun potentieel om te leren. Diagnostiek in de leerlingbeleiding zou daarom inzicht moeten geven in hoe een kind begeleid kan worden in het verder ontwikkelen van zijn of haar sterke kanten terwijl het tegelijkertijd handvatten biedt voor het ondersteunen…

An assessment approach that tailors to children’s instructional needs

Promotor: J.W. van Holten

Hoe beinvloed de structuur van één enkel gen de activiteit van genen die gevoelig zijn voor hormonen?

Promotor: Prof.dr. S.F. Portegies Zwart

Promotor: W.Th.F. den Hollander

Promotor: Prof.dr. H.J.M. de Groot, Co-promotor: Francesco Buda

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Het artikel 'Flexible updating of dynamic knowledge structures' met bijdrage van Franziska Richter van Cognitieve Psychologie is uitgebracht door Nature.

Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Developing methodes to understand the evolution of patches in natural ecosystems

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

Het onderzoek in dit proefschrift kijkt naar de rol van het locus ceuruleus - noradrenalinesysteem in verscheidene aspecten van menselijke cognitie, en de modulatie van de staat van het brein.

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Remus Dame

Promotor: Prof.dr. G.J. Kroes

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Unconstrained day-to-day activities are difficult to quantify and how the corresponding movements shape the brain remain unclear. Read more

De negende Network Europe Conference in Edinburgh werd in juni 2017 gehouden en was georganiseerd door het Europa Instituut in Zurich.

Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

Promotie

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

Promotor: Prof.dr. B.R. Katzy

Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.

Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

Promotor: Prof.dr. M. Danhof

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Promotie

Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone