1,247 zoekresultaten voor “controlled human infections” in de Publieke website
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Computational modeling of mycobacterium infection and innate immune reponse in zebrafish
Promotor: Prof.dr. J.N. Kok
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Reagent Controlled Synthesis of 1,2-cis-Oligosaccharides
This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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PhD candidate, Cryo-electron microscopy of mycobacterial infection
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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Controlled human infection models as a tool for malaria and schistosomiasis vaccine research
Promotie
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Molecular electronics: Controlled manipulation, noise and graphene architecture
Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.
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Chemokine signaling mechanisms underlying inflammation and infection control: insights from the zebrafish model
This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.
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extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Humans of Psychology
Humans of Psychology plaatst studenten en medewerkers van het Instituut Psychologie in de spotlight. Of het nu gaat om inspirerend onderwijs, bijzonder onderzoek, een publieksbijeenkomst, open science of een bestseller. Neem een kijkje achter de schermen.
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immunization with Plasmodium falciparum sporozoites in the controlled human malaria infection model
Promotie
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Effects of human pressures on aquatic invertebrate
What are interactive effects of human pressures on aquatic communities?
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Betere vaccins tegen malaria en tuberculose
De infectieziektes malaria en tuberculose zijn verantwoordelijk voor 2.1 miljoen dodelijke slachtoffers per jaar. Op dit moment testen Leidse onderzoekers een nieuw tuberculosevaccin.
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modular goldnanoparticles for glycan-based immune-interventions of worm infections
Chiodo
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Researcher: Rapid MS-detection and characterization of variants of viral infections (1.0 fte)
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Researcher: Rapid MS-detection and characterization of variants of viral infections (1.0 fte)
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Human iPSC Hotel
Het LUMC iPSC Hotel biedt de generatie van research grade humane geïnduceerde pluripotente stamcellen (iPSC's) uit verschillende weefselbronnen met behulp van de modernste herprogrammeringstechnieken.
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Frontex and Human Rights
Melanie Fink, Postdoctoraal Onderzoeker bij het Europa Instituut van de Universiteit Leiden, heeft haar boek Frontex and Human Rights, Responsibility in 'Multi-Actor Situations' under the ECHR and EU Public Liability Law gepubliceerd. Dit boek is gebaseerd op haar proefschrift, dat zij in december 2017…
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Frontex and Human Rights Responsibility
Woensdag 13 december verdedigde Melanie Fink haar proefschrift ‘Frontex and Human Rights: Responsibility in “Multi-Actor Situations” under the ECHR and EU Public Liability Law’.
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Can tigers survive in human-dominated landscapes?
S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.
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Stage - Human Resource Frontoffice
Administratief Shared Service Centre
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Human Rights Elephants in an Era of Globalisation: Commodification, Crimmigration, and Human Rights in Confinement
Op 21 januari 2020 verdedigde Patrick van Berlo zijn proefschrift 'Human Rights Elephants in an Era of Globalisation: Commodification, Crimmigration, and Human Rights in Confinement'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.P. van der Leun en prof.mr.dr. M.A.H. van der Woude.
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Digital Media in Human Development (MSc)
De masterspecialisatie Digital Media in Human Development gaat over kansen en uitdagingen van digitale media in opvoeding en onderwijs.
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Applied Neuroscience in Human Development (MSc)
Voor wie geïnteresseerd is in de relatie tussen neuro-cognitieve en biologische factoren enerzijds en leren, gedrag en emoties anderzijds.
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The Encyclopedia of Global Human Migration
The Encyclopedia of Global Human Migration biedt een complete verkenning van de prominente thema's, gebeurtenissen en theoretische onderbouwingen van de verplaatsingen van menselijke bevolkingsgroepen van de prehistorie tot heden.
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Leids Universitair Medisch Centrum
Het LUMC staat voor de verbetering van de gezondheidszorg en de gezondheid van mensen. Deze missie brengen de medewerkers van het LUMC dagelijks in de praktijk met toonaangevend onderzoek, vernieuwend onderwijs en optimale, innovatieve zorg.
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Human-lion conflict around nairobi national park
Large carnivore population is globally declining as a result of the fragmentation of habitat, large prey depletion and retaliatory killing by pastoralists.
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Humans of Humanities
In de serie Humans of Humanities, lichten wij iedere twee weken een van onze wetenschappers, medewerkers of studenten uit.
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Using Agent-Level Factors to Explain Variation in Human Rights Promotion Strategies
In dit artikel stelt Tom Buitelaar een systematisch kader voor om het effect van individuele kenmerken van vredeshandhavers op het gedrag van grondpersoneel bij VN-vredesoperaties te analyseren.
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Hoofd HRM / Hoofd Human Resources
Wiskunde en Natuurwetenschappen
- Hoofd HRM / Hoofd Human Resources
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Human-wildlife Interactions in the Western Terai of Nepal
Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.
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attention only for people with HIV and depressive symptoms: A randomized controlled trial
We found that, next to the effectiveness of the intervention, it’s also very likely that the intervention is cost-effective compared to attention only.
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The future of AI is human
Van zelfrijdende auto’s tot innovatieve medicijnontwikkeling, kunstmatige intelligentie (AI) gaat ons leven op uiteenlopende manieren fundamenteel veranderen. Onze computerwetenschappers bestuderen de technologie op een diep en fundamenteel niveau. Maar we zoeken ook naar medische toepassingen en antwoorden…
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Targeting Human Proteasomes: Substrates, Inhibitors and Prodrugs
Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.
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Voorlichtingsactiviteiten
Kom naar onze online en oncampus events om ons beter te leren kennen!
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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European and International Human Rights Law (Advanced LL.M.)
Leiden University’s Master of Law in European and International Human Rights Law (L.L.M.) looks at the various protection mechanisms applied to human rights across different political, social and cultural settings.
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Ecology and conservation of spotted hyena in human dominated landscapes in northern Ethiopia
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. H. Leirs (Univ. Antwerpen)
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Human skin equivalents for atopic dermatitis: investigating the role of filaggrin in the skin barrier
Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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based toxicity assessment: towards quantitative risk prediction in humans
Promotor: Prof.dr. M. Danhof
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Online Master’s Experience European and International Human Rights Law
Studievoorlichting, Online Master’s Experience
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken