Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.

This thesis discusses the discovery potential of Intensity Frontier experiments.

GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

Lezing, This Week's Discoveries

What happens to electrical waves that have to cross gaps in insulation material around nerves in the human body

A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

Mosselen in mosselbedden vormen een patroon dat lijkt op de organisatie van moleculen en atomen in materialen als brons, staal of rubber. Dit gedrag kan dan ook worden beschreven met hetzelfde wiskundige model.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

In this work, we attempt to answer the question:

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

In het Scheepvaartmuseum van Amsterdam bevindt zich een getuigd model van een driemasterschip uit de tweede helft van de zestiende eeuw: het oudste scheepsmodel in de museumcollectie. Historicus Louis Sicking deed in opdracht van het museum onderzoek naar dit bijzondere object.

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

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Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Promotor: W. T. F. den Hollander, F. H. J. Redig

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Shabaz Sultan en Simon Portegies Zwart, met de hulp van Vincent Icke, hebben één van de tien Surf Innovation Challenge Awards gewonnen voor hun onderzoek naar 'Interactive high-performance laboratory for Chaos'. De winnaars hebben een geldprijs van 10.000 euro ontvangen en krijgen 6 maanden (tot 1 juni…

Media & interactie is waar kunstmatige intelligentie en machine learning samenkomen met filosofie, cognitieve wetenschap en de creatieve kunsten. Voorbeelden van onderzoeksvragen in dit domein zijn: ‘Kan een algoritme naar menselijke maatstaven creatief zijn?', 'Kunnen creatieve processen, zoals het…

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Hetterscheid

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Het onderzoeksgebied Natural Computing is uitgegroeid tot een onderzoeksgebied met een spannende interactie tussen informatica en natuurwetenschappen en een belangrijke katalysator voor deze twee-weg interactie. Dit driedelige handboek van meer dan 2000 pagina's is een belangrijk verslag van deze belangrijke…

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Promotor: Prof.dr. M. Danhof

Promotor: Prof.dr. K.J. Batenburg

Promotor: A.W. van der Vaart

Galaxies form and live inside dark matter haloes. As a consequence, they are exposed to the tidal fields generated by the surrounding matter distribution: this imprints a preferential direction to the galaxy shapes, which leads to a coherent alignment on physically close galaxies, called intrinsic a…

Promotor: Prof.dr. J.N. Kok

Promotor: J. Schaye

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

We consider the propagation of electrical signals through nerve fibres.