252 zoekresultaten voor “clinical pharmacology” in de Publieke website
-
Onderzoek
The aim of our research program is to better understand the aetiology and course of mood, anxiety and trauma and stressor-related disorders and to test and improve treatments for these disorders.
-
Assistant Professor in Neuropsychology
Sociale Wetenschappen, Psychologie
-
Marlies Reinders
Integratie van MOOC in campus
-
De 3 V's
We doen zo min mogelijk dierproeven. Daarom toetsen we voor elk onderzoek of er zo veel mogelijk rekening is gehouden met de zogeheten 3 V’s: vervanging, vermindering en verfijning. De Instantie voor Dierenwelzijn adviseert wetenschappers hierin. Omdat we personeel trainen en nascholing bieden, bereiken…
-
Colloquium - Understanding social motivation: a neuro-pharmacological and clinical account
Lezing
-
Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetic models
Promotie
-
Medicinale cannabis in kaart gebracht
Sinds ongeveer tien jaar kunnen artsen medicinale cannabis voorschrijven. Maar hoe vaak en aan bijvoorbeeld wie dit gebeurt, was nooit echt duidelijk. De Leidse bio-farmaceutisch onderzoeker Arno Hazekamp heeft dit samen met zijn Utrechtse collega farmaco-epidemioloog Rob Heerdink in kaart gebracht.…
-
Optimizing Breast Reconstructive Surgery in the Netherlands Using Clinical Audit Data
Promotie
-
Image guided surgery: clinical validation of lesion identification technologies and exploration of nerve sparing approaches
Promotie
-
skin inflammation with a novel dermatology toolbox for early phase clinical drug development
Promotie
-
On the pathogenesis and clinical outcome of ANCA-associated vasculitis
Promotie
-
Clinical and Immunological Outcome after Paediatric Stem Cell Transplantation for Inborn Errors of Immunity
Promotie
-
Antiepileptic and antitumor treatment in brain tumor patients: impact of clinical and radiological outcome
Promotie
-
Early phase clinical drug development for HPV-induced disorders: novel tools and treatments
Promotie
-
The Forefoot in Early Rheumatoid Arthritis: Anatomy, Imaging and Clinical Aspects
Promotie
-
Matters of the heart: clinical studies in paediatric cardiac intensive care
Promotie
-
Clinical aspects of the relation between diabetes mellitus and kidney disease: from hyperfiltration to dialysis
Promotie
-
Advanced clinical applications of cardiac computed tomography and novel echocardiographic modalities
Promotie
-
Understanding clinical outcome in patients with pituitary disease: a biopsychosocial approac
Promotie
-
Hereditary breast cancer and the clinical significance of variants in the BRCA1 and BRCA2 genes
Promotie
-
Advanced echocardiography and clinical surrogates to risk stratify and manage patients with structural heart disease
Promotie
-
Clinical determinants of red cell alloimmunízation: implications for preventative antigen matching strategies
Promotie
-
Functional imaging of the brain vasculature in pre-clinical models of amyloidosis
Promotie
-
Advances in diagnostics of respiratory viruses and insight in clinical implications of rhinovirus infections
Promotie
-
Individual Clinical Advanced decision-making And Risk Evaluation for Ewing sarcoma
Promotie
-
course of Clinically Suspect Arthralgia and Early Rheumatoid Arthritis: Clinical features, imaging and genetics
Promotie
-
Development and use of biomarkers in clinical development of new therapies for chronic airway disease
Promotie
-
Effect of inhaled corticosteroids on clinical and pathological outcomes in COPD
Promotie
-
Fluorescence-guided cancer surgery, using clinical available and innovative tumor-specific contrast agents
Promotie
-
The role of glomerular filtration and active tubular secretion in predicting renal clearance in children using population pharmacokinetic and
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
-
Masters
Heb jij een bachelordiploma op zak en wil je een masteropleiding volgen aan een Nederlandse universiteit van wereldklasse? Met bijna 80 masteropleidingen vind je bij de Universiteit Leiden de master die bij je past.
-
Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
-
Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
-
Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
-
Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
-
Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
-
PLGA-based particulate vaccine delivery systems for immunotherapy of cancer
Promotores: W. Jiskoot, F. Ossendorp
-
Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
-
The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
-
Novel regulators of prostate cancer stem cells and tumor aggressiveness
Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm
-
The road to insurmountability: Novel avenues to better target CC Chemokine receptors
This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.
-
Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
-
High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier
-
Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
-
Algorithm for Structural Variant Detection
Promotie
-
Onderzoeksteam
Achter de schermen werken er veel verschillende mensen mee aan het Cool Little Kids project en het bijbehorende onderzoek. Zie hieronder een overzicht van het onderzoeksteam.
-
in vivo: Discussions on the anatomy, involvement in cognition and clinical applications
Promotie
-
Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
-
How to scale clearance from adults to children for drugs undergoing hepatic metabolism?
The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.
-
Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.