150 zoekresultaten voor “cardiovascular disease” in de Publieke website
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PhD candidate “Personalized rewards of lifestyle changes in cardiovascular diseases”
Sociale Wetenschappen, Psychologie
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Macrophage activation and cholesterol in atherosclerosis development
Current therapies for patients with atherosclerosis are targeted primarily on reducing blood cholesterol, but this fails to prevent a large number of cardiovascular events.95 In order to identify new therapeutic strategies for treating atherosclerosis, it is important to study the interactions between…
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Cardiovascular compromise in monochorionic twins
Promotie
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Macrophage activation and cholesterol in atherosclerosis development
Promotores:Th.J.C. van Berkel, M. van Eck
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Future drugs in atherosclerotic cardiovascular disease
Promotie
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glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Novel insights into blood markers and cardiovascular disease
Promotie
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Efficacy, safety and novel targets in cardiovascular disease
Promotie
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
- Secondary cardiovascular prevention in old age
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Creating a continuum of care: smart technology in patients with cardiovascular disease
Promotie
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and the McCune-Albright syndrome: various aspects of a heterogeneous disease
Promotie
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Preclinical validation of putative targets in cardiovascular and metabolic disease
Promotie
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LLP-studenten aan de slag bij Janssen voor een World Without Disease
Een wereld zonder ziekte: toekomst of illusie? In ieder geval het nastreven waard, vinden ze bij Janssen, dat de mogelijkheden voor zo’n wereld daarom onderzoekt. Studenten van het Leiden Leadership Programme brachten voor het bedrijf enkele dilemma’s in kaart die daarbij een rol kunnen spelen.
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biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
- Circulating cells as biomarkers in cardiovascular
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Carotid Imaging In Cardiovascular Risk Assessment
Promotie
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Understanding disease suppressive soils
Promotie
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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The synthesis of chemical tools for studying sphingolipid metabolism
Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.
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Clinical Advances in Cardiovascular Magnetic Resonance Imaging and Angiography
Promotie
- Suicidality in Huntington's disease
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Chronic obstructive pulmonary disease
Promotie
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Huntington Disease and other Polyglutamine Diseases: Using CAG repeat variations to explain missing heritability
Promotie
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Stromal cells in Inflammatory Bowel Disease
Promotie
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Quantitative MRI in Obesity and Reno-Cardiovascular Function
Promotie
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Knowledge discovery methods for Huntington’s Disease
Promotie
- Mesenchymal Stromal Cell in Pediatric Disease
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Blood and biomarkers in Huntington’s Disease
Promotie
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Surgical therapy of organic mitral valve disease
Promotie
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The Huntingtin protein in Huntington disease
Promotie
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Neuropsychiatric phenomena in Huntington's disease
Promotie
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Music therapy in Huntington's disease
Promotie
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This Week’s Discoveries | 6 June 2017
Lezing
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Modeling Vascular Diseases Using Human Induced Pluripotent Stem Cells
Promotie
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Keeping the heart in mind: cardiovascular determinants of neurocognitive functioning in old age
Promotie
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Sex-specific post-transcriptional regulation of cardiovascular complications in diabetes
Promotie
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Systemic and cerebral hemodynamics in response to cardiovascular challenges - the heart brain connection
Promotie