Multicellular giant algae Chara species have been widely used in physiological studies for decades.

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

Promotor: M. Franx, Co-Promotor: I.F. Labbé

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

In this thesis, we present new laboratory data of interstellar dust analogues.

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Possible improvements for the assessment of abiotic depletion in LCA.

M. Danhof, Co-promotores: J. Freijer, A. Yassen

Promotores: J. Kok, M. Chaudron (Chalmers University)

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

Promotores: B. Erez, P. Stevenhagen, Co-Promotor: B. de Smit

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

Promotie

Hieronder kun je een antwoord vinden op de meestgestelde vragen over de master. Wordt jouw vraag niet beantwoord? Neem gerust contact met ons op voor een gepersonaliseerd antwoord via: masterva@lumc.nl.

Detentie is momenteel de strengste sanctie die in de strafrechtstelsels van de Europese landen wordt toegepast. In de meeste landen is de gevangenispopulatie de afgelopen decennia toegenomen. In Nederland worden jaarlijks meer dan 30.000 mensen opgesloten in de gevangenis van een penitentiaire inrichting…

Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…

In Zuid-Afrika zijn ongelijkheid en geweld de twee grootste problemen. Waar komen die problemen vandaan? Misschien hangen ze samen met rivaliserende groepen, misschien met economische factoren, met overheidsbeleid of met alle drie tegelijk. Om maatschappelijke problemen te begrijpen, is het belangrijk…

Promotie

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Fundamental research in the ALgebra, Geometry And Number Theory

Promotores:Th.J.C. van Berkel, M. van Eck

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

Onderzoekers aangesloten bij het Leiden Leadership Centre zijn actieve leden van het PUPOL netwerk. PUPOL is een internationaal academisch netwerk voor publiek en politiek leiderschap. Dit netwerk stimuleert de uitwisseling van ideeën en bevordert gezamenlijk onderzoek tussen wetenschappers gericht…

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

This thesis is about cosmological inflation and its relation to observations.

Examining if large scale application of new energy pathways can be constrained by materials and emissions.

Migration imposes special pressures on the meaning, experience and organization of lifecycle rituals. These pressures are felt most strongly by Muslim migrants to Western Europe. In this innovative study, Nathal M. Dessing examines the effects of migration on the life cycle rituals of Moroccan, Turkish…

Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

The cases of building materials, automobility, mushrooms and plastics.

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

This thesis concerns the relation bettween the good reduction of Shimura varieties and the associated loop groups.