112 zoekresultaten voor “breast cancer” in de Publieke website

• RNA splicing in breast cancer progression Onderzoeksoutput

  In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

• Exploring Grainyhead-like 2 target genes in breast cancer Onderzoeksoutput

  The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

• PI3K signaling and adherens junctions in invasive lobular breast cancer Onderzoeksoutput

  Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

• Precision modeling of breast cancer in the CRISPR era Onderzoeksoutput

  The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

• Targeted Therapy for Triple-Negative Breast Cancer Onderzoeksoutput

  The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

• Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice Onderzoeksoutput

  In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

• Dwaipayan Banerjee - Enduring Cancer Agenda - 7 december 2021

  Lezing, Online webinar

• Novel regulators of prostate cancer stem cells and tumor aggressiveness Onderzoeksoutput

  Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

• Liposome-based synthetic long peptide vaccines for cancer immunotherapy Onderzoeksoutput

  Promotores: Wim Jiskoot; Ferry Ossendorp

• Precision modeling of breast cancer in the CRISPR era Agenda - 16 januari 2020

  Promotie

• Immune cell complexity in the tumor microenvironment of breast cancer Agenda - 22 oktober 2019

  Promotie

• Uncovering vulnerabilities in triple-negative breast cancer Agenda - 31 oktober 2019

  Promotie

• A comprehensive approach for quality assurance of breast cancer care Agenda - 22 september 2021

  Promotie

• PLGA-based particulate vaccine delivery systems for immunotherapy of cancer Onderzoeksoutput

  Promotores: W. Jiskoot, F. Ossendorp

• xenograft model: identification of novel mechanisms driving prostate cancer metastasis Onderzoeksoutput

  Prostate cancer (PCa) is one of the most prevalent cancer in males.

• improve treatment strategies for patients with hepatic or pancreatic cancer Agenda - 1 december 2021

  Promotie

• Tailoring adjuvant therapy for hormone receptor-positive early breast cancer Agenda - 31 mei 2018

  Promotie

• of actomyosin contraction as a driving force of invasive lobular breast cancer Agenda - 3 december 2020

  Promotie

• Ductal carcinoma in situ of the breast: cancer precursor or not? Agenda - 10 maart 2020

  Promotie

• Ductal carcinoma in situ and invasive breast cancer: diagnostic accuracy and prognosis Agenda - 9 september 2021

  Promotie

• uncover genes driving tumorigenesis and therapy resistance in human breast cancer Agenda - 22 mei 2019

  Promotie

• Patterns of care and prognosis of older women with breast cancer Agenda - 14 februari 2018

  Promotie

• Integrating clinicopathological and molecular data in the breast cancer patient: Towards precision medicine Agenda - 19 mei 2016

  Promotie

• Optimizing breast cancer survival models based on conventional biomarkers and stromal parameters Agenda - 26 september 2017

  Promotie

• The Effects of Breast Cancer Therapy on Estrogen Receptor Signaling Throughout the Body Agenda - 8 juni 2017

  Promotie

• Shared decision-making about treatments for early breast cancer: preferences of older patients and clinicians Agenda - 13 november 2018

  Promotie

• 
  Haico van Attikum Hoogleraar Humane Genetica, in het bijzonder van chromatine en DNA-reparatie

  Faculteit Geneeskunde

• Erik Danen benoemd tot hoogleraar Cancer drug target discovery Nieuws - 24 april 2018

  Met ingang van 1 april 2018 is Erik Danen benoemd tot hoogleraar Cancer drug target discovery bij het Leiden Academic Centre for Drug Research (LACDR). Zijn vakgebied is celbiologie van kanker, waarin hij zich richt op de achterliggende mechanismen bij uitzaaiingen en resistentie voor behandelingen.

• Modelling the role of cytotoxic T lymphocytes in tumour regression Onderzoeksoutput

  Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

• Role of integrin adhesions in cellular mechanotransduction Onderzoeksoutput

  Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

• 
  Judith Bovée Hoogleraar Pathologie, in het bijzonder de pathologie van bot- en wekedelentumoren

  Faculteit Geneeskunde

• The Metallophilic Interaction between Cyclometalated Complexes: Photobiological Applications Onderzoeksoutput

  In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.

• 
  Lioe-Fee de Geus-Oei Hoogleraar Radiologie

  Faculteit Geneeskunde

• TechTalk Cancer Diagnostics & Therapy Agenda - 16 november 2017

  Lezing

• Cancer drug target discovery Agenda - 10 mei 2019

  Oratie

• Brachytherapy for rectal cancer Agenda - 8 juni 2021

  Promotie

• Molecular alterations in endometrial cancer Agenda - 20 april 2017

  Promotie

• Glycomic Signatures of Colorectal Cancer Agenda - 24 januari 2017

  Promotie

• Light and nanoparticles against cancer Agenda - 13 april 2021

  Lezing, This Week's Discoveries

• Modulating the behaviour of pancreatic tumour cells Onderzoeksoutput

  Promotores: Prof.dr. M.K. Richardson, Prof.dr. H.P. Spaink. Co-promotor: C.P. Bagowski

• Killing cancer cells with metals and light Agenda - 21 maart 2019

  Lezing

• DNA repair in chromatin: the cancer connection Agenda - 31 oktober 2019

  Lezing

• Surgical outcome of colorectal cancer screening Agenda - 14 januari 2021

  Promotie

• The use of light in cancer immunotherapy Agenda - 19 april 2018

  Promotie

• Frailty and outcomes in older cancer patients Agenda - 29 september 2021

  Promotie

• Therapeutic targeting of immune-escaped cancers Agenda - 18 februari 2020

  Promotie

• Cancer vaccine strategies to improve immunotherapy Agenda - 21 oktober 2021

  Promotie

• Immune-based therapies in ovarian cancer Agenda - 13 juni 2017

  Promotie

• Mechanisms of Ewing sarcoma metastasis Onderzoeksoutput

  Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

• Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors Onderzoeksoutput

  Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.