De BioMedical Metabolomics Facility Leiden (BMFL) biedt een zeer gestructureerde omgeving voor geavanceerd metobolomicsonderzoek. BMFL is gebaseerd op volledig gevalideerde, moderne platforms die gezamenlijk het gehele menselijke metabolisme beslaan.

De Engelstalige master Biomedical Sciences gaat over alle normale en abnormale processen in het menselijk lichaam. Zo leer je ziektes beter te begrijpen, bestaande therapieën te verbeteren of nieuwe therapieën te bedenken. Naast het algemene programma dat zich toespitst op de wetenschappelijke onderzoekscomponent,…

Promotor: M.A.G.J. Orrit

The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.

This thesis focuses on the study of transient and variable radio sources in the universe.

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Wiskunde en Natuurwetenschappen

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Promotor: Prof.dr. C.U. Keller

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Promotor: A. Kros

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

Promotie

Promotor: V. Vitelli, Co-promotor: J. Paulose

Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

Hoogleraar Fons Verbeek, verbonden aan de informatica- en biologie-instituten van de Universiteit Leiden, heeft de fascinatie om alles wat we niet direct kunnen zien, toch in beeld te brengen. Op SleutelstadFM vertelt hij dat door het omrekenen van 2 dimensionale (2D) beelden naar 3 dimensionale (3D)…

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

'Ik zou nooit behandeld willen worden door een computer', zegt Boudewijn Lelieveldt. Hij is binnen Radiologie hoofd van het Laboratorium voor Klinische en Experimentele Beeldverwerking, en Medical Delta hoogleraar bij de Bio-informatica-groep aan de TU Delft. Hoe intelligent systemen ook zijn, een arts…

Huub de Groot

Hoe breng je larven van de zebravis microscopisch in beeld? De nieuwe gratis online cursus ‘Imaging the Vertebrate embryo’ leert je er alles over. Leidse promovendi Salomé Muñoz Sánchez en Radoslaw Gora werkten mee aan de cursus.

De masteropleiding Vitality and Ageing is dit jaar beoordeeld als topopleiding in de Keuzegids Masters. Ook Biomedical Sciences staat op de eerste plaats. Farmacie stijgt naar de tweede plaats en tussen de masteropleidingen Geneeskunde is opnieuw weinig kwaliteitsverschil.

Marin van Heel, emeritus hoogleraar bij het Instituut Biologie Leiden (NeCEN), is een van de winnaars van de Wiley Prize in Biomedical Sciences 2017. Deze jaarlijkse onderscheiding eert belangrijke bijdragen die nieuwe onderzoeksvelden ontsluiten of concepten hebben bevorderd in een biomedische disc…

Promotor: B. van de Water

The LIACS Media Lab has received a research grant from the worldwide leading graphics hardware company NVIDIA. The grant exists of newly developed hardware utilizing thousands of processors. LIACS researchers will use it to investigate deep learning in understanding imagery from sources such as MRI…

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

Oratie

Diploma-uitreiking

Diploma-uitreiking

Diploma-uitreiking

Diploma-uitreiking

In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.