54 zoekresultaten voor “bacterial chitinase” in de Publieke website
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Ecological functioning of bacterial chitinases in soil
Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)
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Small-molecule inhibitors of bacterial metallo-β-lactamases
The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Assemblage and functioning of bacterial communities in soil and rhizosphere
Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae
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Structural characterization of bacterial proteins involved in antibiotic resistance and peptidoglycan biosynthesis
This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.
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Synthesis of phosphodiester-containing bacterial cell wall components: teichoic acids, capsular polysaccharides and phosphatidyl glycerol analogues
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Solvent tolerance mechanisms in Pseudomonas putida
Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.
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Small-molecule inhibitors of bacterial metallo-β-lactamases
Promotie
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Effect of Nanoparticles on Microbial Catabolism and Community Structure using Biolog techniques
1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?
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The rhizomicrobiome of Sorghum ; impact on plant growth and stress tolerance
The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Modulation of plant chemistry by rhizosphere bacteria
Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Promotie
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Host-Directed Therapy for Intracellular Bacterial Infections
Promotie
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Growth-induced self-organization in bacterial colonies
Promotie
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Promotie
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Assemblage and functioning of bacterial communities in soil and rhizosphere
Promotie
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Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
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Anthropogenic effects on links between macro-invertebrate diversity and ecosystem functioning
How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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NGL-lezing: Zooming in on bacterial behaviour
Lezing
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Promotie
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Structural characterization of bacterial proteins involved in antibiotic resistance and peptidoglycan biosynthesis
Promotie
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus
Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame
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Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?
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Synthesis of Phosphodiester-containing Bacterial Cell Wall Components: Teichoic Acids, Capsular Polysaccharides and Phosphatidyl Glycerol analogues
Promotie
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Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans
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Marine bacteria hold the key to a sustainable future
Lezing, This Week's Discoveries
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Lezing Ariane Briegel uitgesteld
Wegens de stroomstoring in de middag van 15 maart is de NGL-lezing door Ariane Briegel 'Zooming in on bacterial behaviour' op die datum afgelast.
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Archief
Benieuwd naar de afgelopen lezingen? In het archief bewaren wij de presentaties en eventuele verslagen van onze lezingen.
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Helder beeld van bacteriën
Een bacterie supersnel bevriezen, om de structuur van buiten en binnen natuurgetrouw in beeld te brengen. Hoogleraar Ultrastructuurbiologie Ariane Briegel kwam speciaal hiervoor naar Leiden: de Universiteit Leiden is een van de weinige instituten wereldwijd waar de benodigde apparatuur beschikbaar is.…
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This Week’s Discoveries | 2 April 2019
Lezing
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Bacteriën bevriezen en fotograferen
Hoe weet een bacterie waar er voedsel is in zijn omgeving? En hoe beweegt die bacterie vervolgens naar dat voedsel toe? Hoogleraar Ultrastructuurbiologie Ariane Briegel nam het publiek mee op een microscopische reis tijdens haar lezing ‘Zooming in on bacterial behaviour’ voor het Natuurwetenschappelijk…
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Vijftig Tinten Stress
De uitdaging: een tool ontwikkelen die chemische stoffen detecteert die op zichzelf niet-dodelijke stress geven aan bacteriën, maar gecombineerd wel dodelijk zijn. Een team van dertien Leidse studenten nemen deze uitdaging aan in de jaarlijkse ‘international Genetically Engineered Machine’ (iGEM) competitie…
- This Week’s Discoveries | 23 February 2016
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This Week's Discoveries | 7 July 2020
Lezing
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Origins of antibiotic resistance
Lezing, Van Leeuwenhoek Lecture on BioScience
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In the Spotlight - Biology Seminars Leiden
Lezing
- Lezingen Natuurwetenschappelijk Gezelschap Leiden
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Joan van der Waals colloquium
Lezing
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Van Leeuwenhoek Lecture on BioScience: DNA Sequencing Technology
Lezing
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Drie LUF-subsidies voor Leidse bètawetenschappers
In strijd tegen kanker, antibiotica-resistentie en wegwerpplastic: Ahmed Ali, Fredj Ben Bdira en Valerio Barbarossa ontvangen een LUF-subsidie voor hun innovatieve en maatschappelijk relevante onderzoek. Deze subsidies voor academisch talent vormen vaak een belangrijke springplank naar aanvragen bij…