Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans

Promotor: R. Gill, Co-promotor: P. Massart

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

Op woensdag 5 juni gaf Kalin Anev Janse, Secretaris-Generaal en lid Raad van Bestuur van het European Stability Mechanism (ESM), een lezing getiteld 'Bridging decision-making: a new direction for Europe? Prioritising financial stability: the European Stability Mechanism and the Banking Union'.

In this thesis three different topics in number theory are studied.

In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.

This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…

In this thesis we study bistable reaction-diffusion equations on lattice domains.

We consider the propagation of electrical signals through nerve fibres.

Lezing

Promotor: W.Th.F. den Hollander

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Lezing

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

Promotores: R. Tijdeman, K.J. Batenburg

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer

Promotie

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Promotor: A.W. van der Vaart

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone

The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.

Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

The focus of the dissertation

Promotor: A. Kros