21 zoekresultaten voor “antibiotics” in de Publieke website

• Environmental and metabolomic study of antibiotic production by actinomycetes Onderzoeksoutput

  Promotor: Prof.dr. G.P. van Wezel

• Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity Onderzoeksoutput

  The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

• Structural characterization of bacterial proteins involved in antibiotic resistance and peptidoglycan biosynthesis Onderzoeksoutput

  This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

• Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches Onderzoeksoutput

  Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

• Another Brick in the Wall: The role of the actinobacterial cell wall in antibiotic resistance, phylogeny and development Onderzoeksoutput

  Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

• Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning Onderzoeksoutput

  The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

• Origins of antibiotic resistance Agenda - 21 februari 2019

  Lezing, Van Leeuwenhoek Lecture on BioScience

• Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children Onderzoeksoutput

  Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

• Chemical Biology Lezing: Biosynthesis and Engineering of Cyclic Peptide Antibiotics Agenda - 26 oktober 2017

  Lezing

• Research Science Communication and Society

  The mission of our group is understanding how science communication works to improve the interaction between science and society.

• Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity Agenda - 11 maart 2021

  Promotie

• Structural and biochemical analysis of antibiotic-target interactions Agenda - 8 december 2020

  Promotie

• Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes Onderzoeksoutput

  Almost all bacteria are enveloped by a cell wall that provides cellular protection.

• Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans Onderzoeksoutput

  Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

• 1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides Onderzoeksoutput

  Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

• Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches Agenda - 26 oktober 2016

  Promotie

• Bètawetenschappers laten je het licht zien tijdens de Middag en Nacht van Ontdekkingen Nieuws - 9 september 2019

  Licht en donker, dat is dit jaar het thema van de Nacht van de Ontdekkingen van zaterdag 21 september op zondag 22 september 2019, in de Leidse binnenstad. Het programma belooft performances, lezingen, workshops en rondleidingen op het gebied van wetenschap, kunst en cultuur. Dit jaar is er voor het…

• This Week’s Discoveries | 13 March 2018 Agenda - 13 maart 2018

  Lezing

• This Week’s Discoveries | 8 November 2016 Agenda - 8 november 2016

  Lezing

• Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes Agenda - 17 september 2019

  Promotie

• This Week's Discoveries | 10 March 2020 Agenda - 10 maart 2020

  Lezing