236 zoekresultaten voor “adverse outcome path” in de Publieke website
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Personalised pharmacotherapy in paediatric epilepsy : the path to rational drug and dose selection
The path to rational drug and dose selection
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Personalised medicine for multiple outcomes: methods and application
The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.
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Into the Darkness: Forging a Stable Path Through the Gravitational Landscape
In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.
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“This Path Is Full of Thorns”: Narrative, Subjunctivity, and HIV in Indonesia
In this article, Samuels focuses on the active fostering of subjunctivity in processes of narrative worldmaking. Drawing extensively from the narrative of an HIV‐positive woman in Indonesia, she shows that by subjunctively leaving open multiple narrative trajectories and future possibilities, individuals…
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Paving the path between low- and high-mass star formation: dynamics probed by Herschel far-infrared spectroscopy
Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)
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Healthcare improvement based on learning from adverse outcomes
Promotie
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Induced substitutions
Promotor: R. Tijdeman, Co-promotor: C. Kraaikamp
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Het toegevoegde risico van grootte
Wat zijn de risico's van nanodeeltjes?
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Prediction of adverse health outcomes in older patients visiting the Emergency Department: the APOP study
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gatekeeper: incidental negative cues stimulate choices with negative outcomes”
Promovendus Niek Strohmaier heeft een artikel gepubliceerd in het gerenommeerde tijdschrift Cognition & Emotion, met de titel: “Bypassing the gatekeeper: incidental negative cues stimulate choices with negative outcomes”. Dit artikel onderzoekt in brede zin welke factoren van invloed zijn op de keuzes…
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Algorithms for analyzing and mining real-world graphs
Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters
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Exposure and health Assessment of Persistent Organic Pollutants (POPs) at e-waste recycling site among workers in the informal sector in Nigeria
Do e-waste workers display enhanced effects of adverse health effects due to informal e-waste processing in Nigeria? Is there a difference between the health outcomes of the exposed and the control groups? Are there difference in health effects within and between job groups (collectors, dismantlers,…
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Surviving embryogenesis: The extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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Predicting outcome after liver transplantation
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Clinical Outcomes in Bariatric Surgery
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Clinical outcomes of modern lamellar keratoplasty techniques
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Surgical outcome of colorectal cancer screening
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Mortality and other outcome measures in osteoarthritis
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Tactile Paths: on and through notation for improvisers
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Health and Imaging Outcomes in Axial Spondyloarthritis
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Towards a patient-driven approach to adverse events of targeted agents in oncology
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Monitoring Anesthesia: Optimizing Monitoring Strategies to Reduce Adverse Effects of Anesthetic Drugs on Ventilation
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Prognostics of outcome of total knee replacement
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Understandig Sponsorship Involvement Outcomes in Partnership Models
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Cognitive Bias in the Judgment of Business Valuations and Valuators
Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.
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Better Predictions when Models are Wrong or Underspecified
Promotor: P.D. Grünwald
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Understanding the uptake and internal distribution of metallic nanoparticles in Danio rerio larvae
The aim is to discover where differently shaped metal nanoparticles distributes in Danio rerio, linking the distribution with genomic responses and so come up with a Mode of Action.
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Rosema & Louwerse, ‘Response scales in Voting Advice Applications’
Stemwijzers—applicaties die kiezers helpen te bepalen welke partij of kandidaat het beste past bij hun politieke voorkeur—spelen een steeds belangrijker rol in verkiezingen. De politicologen Martin Rosema (Universeit Twente) en Tom Louwerse (Universiteit Leiden) onderzoeken of het ontwerp van deze publicaties…
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Insolvency Office Holder-project
It researches (the possibilities for) the development of a set of principles and best practices for insolvency office holders by comparing multilateral treaties and soft law recommendations and national legislation within Europe.
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Long-term neurodevelopmental outcome after fetal therapy
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The role of water in hydrogen electrocatalysis
Promotor: M.T.M. Koper, Co-promotor: L. Juurlink
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Risk factors and outcome of clinical pancreas transplantation
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Measuring, comparing and improving clinical outcomes in gastrointestinal cancer surgery
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Personalised medicine for multiple outcomes: methods and application
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Prediction of outcomes in patients with heart failure
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ANCA-associated vasculitis: On clinical management and renal outcome
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Value of outcomes research in colorectal cancer care
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Risk factors and outcome measures in hand and knee osteoarthritis
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Cleared for take-off, Game-based learning to prepare airline pilots for critical situations
Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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eScience subsidie voor LION neutrino onderzoek
Het Netherlands eScience Center heeft bekendgemaakt dat het een nieuw Path-Finding Project financiert, dat onder leiding komt te staan van Dr. Dorothea Samtleben van het Leiden Institute of Physics (LION).
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Multimodality imaging in ischemic heart disease, from prevention to outcome
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Into the Darkness: Forging a Stable Path Through the Gravitational Landscape
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A screening based approach to find new paths for targeted treatment in chondrosarcoma
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Preclinical validation of putative targets in cardiovascular and metabolic disease
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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Recommended weighting methods
The project falls in the context of the EU Thematic Strategy on the Sustainable Use of Natural Resources (COM(2005)670). The Institute for Environment and Resources (IES) of the Joint Research Centre (JRC) has developed three sets of decoupling indicators. Such indicators require the definition of a…
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Personalised pharmacotherapy in paediatric epilepsy: the path to rational drug and dose selection
Promotie