373 zoekresultaten voor “nmr spectroscopy” in de Publieke website
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Michel Orrit wins Physica Prize 2016
Michel Orrit was awarded the Physica prize 2016 for his groundbreaking work on single molecule spectroscopy.
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Student projects
We invite you to develop your academic skills by joining our research group and develop your own short term project in the bachelor phase. We offer longer term research projects for master students.
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Crystal Cave
X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.
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Membrane Interactions
Membrane proteins and membrane interactions of proteins are studied by spin label EPR. Intact, native membranes, vesicles of all sizes and nano-disks can be investigated, because the size of the object does not matter in EPR. Whereas solution NMR is limited to micelles (a few nm in diameter), by EPR…
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LIC Lecture: A Distal Regulatory Region of a Class I Human Histone Deacetylase
Lezing
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Towards artificial photosynthesis: resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot
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Michel Orrit receives Spinoza Prize in Royal Theatre
On September 12, Michel Orrit received his Spinoza prize in the Royal Theatre in The Hague from OCW Secretary of State Sander Dekker. With the award comes a budget of 2.5 million euro, to be spent freely on scientific research, and the coveted Spinoza statue. Orrit shared the honor with Eveline Crone…
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From Star-formation to Recombination: Expanding our View of the Radio-Recombination-Line Universe
The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).
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Nobel Prize winner Nicolaas Bloembergen (97) has passed away
We learned of the passing away of Nicolaas Bloembergen, Nobel Prize winner in Physics (1981) at the age of 97.
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Facilities
Our facilities cover:
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Jean-Luc Wolfender
Professor at the School of pharmaceutical sciences, University of Geneva - Switzerland
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Expertise
The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.
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Hye Kyong Kim
PhD at the Natural Product Laboratory, Institute of Biology, Leiden University - the Netherlands
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Microscopy and Spectroscopy on Model Catalysts in Gas Environments
Promotie
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Advanced Imaging and Spectroscopy Techniques for Body Magnetic Resonance
Promotie
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Nanoparticulate Impurities in Pharmaceutical-Grade Sugars and their Interference with Light Scattering-Based Analysis of Protein Formulations
PURPOSE: In the present study we investigated the root-cause of an interference signal (100-200 nm) of sugar-containing solutions in dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) and its consequences for the analysis of particles in biopharmaceutical drug products.
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The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes
The stratum corneum (SC) plays a fundamental role in the barrier function of the skin. The SC consists of corneocytes embedded in a lipid matrix.
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High-resolution integral-field spectroscopy of exoplanets
Promotie
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Early stellar galaxies
Franx
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Maria KazourWiskunde en Natuurwetenschappen
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New funding for the development of a metabolomics resistance test at the IBL
Researchers from the Plant Ecology and Phytochemistry group at the Institute of Biology Leiden (IBL) received an STW (Stichting Technologische Wetenschappen) grant for applied studies in plant herbivore resistance with potential for a novel resistance test.
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Lecture - Molecular disease mechanisms in neurodegeneration: solid-state NMR studies of protein aggregation and mitochondrial lipid oxidation
Lezing
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Promotie
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Redox catalysis for a sustainable energy infrastructure
The main research theme in the group of Dennis Hetterscheid is to understand and mimic bioinorganic multi-electron processes that are relevant to our future energy infrastructure. Reduction of protons generates hydrogen that can be used as a chemical fuel. Alternatively to gaseous hydrogen, the reduction…
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Mesoamerican manuscripts: new scientific approaches and interpretations
Mesoamerican Manuscripts: New Scientific Approaches and Interpretations brings together a wide range of modern approaches to the study of pre-colonial and early colonial Mesoamerican manuscripts. This includes innovative studies of materiality through the application of non-invasive spectroscopy and…
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Spin-label EPR Approaches to Protein Interactions
Promotor: Prof.dr. E.J.J. Groenen
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Gold nanorod photoluminescence: applications to imaging and temperature sensing
Promotor: M.A.G.J. Orrit
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Feedback from deeply embedded low- and high-mass protostars. Surveying hot molecular gas with Herschel
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Natural Products Lab
We focus on natural products research, traditional medicine, ethnobotany and phytochemistry.
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A semisynthetic peptide-metalloporphyrin responsive matrix for artificial photosynthesis
This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.
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In Pursuit of Next-Generation Lipopeptide Antibiotics
Can new variants of daptomycin and the polymyxins be found?
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Terpenoids and terpenoid indole alkaloids in Catharanthus roseus cell suspension cultures
Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte
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Jan Schripsema
Metabolomics group, LCQUI, Universidade UENF, Campos dos Goytacazes/Rio de Janeiro - Brazil
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Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands
Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.
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In vitro and in vivo evaluation of synergistic and opposing effects of Chinese herbal medicine and natural compounds on immuno-modulation.
Can we link multiple components from herbal extracts with their biological activities?
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Projects
Research projects
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Teris van Beek
Dr. at the Department of organic chemistry, Wageningen University - the Nederlands
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In vitro investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Fundamental Research in Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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14th International Metabolomics Workshop
The Basics and Applications to Plant Sciences will be held physical. See below for more information.
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of Pigments on Archaeological Artifacts on site by Mobile Imaging Spectroscopy
Lezing
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FRESH Lecture: Photoelectron spectroscopy in the gas-phase and in liquid-jets
Lezing
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FRESH Lecture: Spectroscopy and Structures of LPMOs: Copper Oxygenases that Oxidize Cellulose
Lezing
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This Week's Discoveries | 14 July 2020
Lezing
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of Gold Nanorods: Applications to Single- Particle Tracking and Spectroscopy
Promotie
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chromatin fibers probed with single-molecule force- and torque-spectroscopy
Promotie
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Fluorescence Correlation Spectroscopy on Electron Transfer Reaction: Probing Inter- and Intramolecular Redox Processes
Promotie
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the AGN environment: new perspectives from high-resolution X-ray spectroscopy
Promotie