This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

Op 3 september 2019 verdedigde Ilektra Antonaki haar proefschrift 'Privatisations and golden shares: Bridging the gap between the State and the market in the area of free movement of capital in the EU'. Het promotieonderzoek is begeleid door promotor prof.dr. S.C.G. Van den Bogaert.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Lezing, Van Leeuwenhoek Lecture on BioScience

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Promotores: B. Erez, P. Stevenhagen, Co-Promotor: B. de Smit

Promotores: T.H. Oosterkamp, N. de Jonge

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

During the course of drug discovery translational steps are made.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Lezing

Lezing

One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Lezing

Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.

Oratie

PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

Hoe leidt zelfredzaamheid tot een afname in samenwerking voor publieke goederen?

Tentoonstelling

Lezing

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

Lezing

The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Het onderzoek van de afdeling Economie is ondergebracht bij meerdere facultaire programma's. Het onderzoek van de afdeling richt zich thans met name op sociaal-economische vraagstukken, rechtseconomie en fiscale economie.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

Promotor: S.J. Edixhoven

Congres/symposium

Op 13 januari 2022 verdedigde Pie Habimana het proefschrift 'Harmful Tax Competition in the East African Community'. Het promotieonderzoek is begeleid door prof.dr. H. Vording en prof.dr. S.C.W. Douma (UvA).

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

This thesis describes the design, characterization and application of dextran based crosslinked network.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Promotor: T.H. Oosterkamp

Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Promotie

Op 7 februari 2019 verdedigde Helena Ursic-Vrabec haar proefschrift 'Uncontrollable: Data subject rights and the data- driven economy'. Het promotieonderzoek is begeleid door promotor prof. dr. S. van der Hof.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Het Europa Instituut van de Universiteit Leiden is één van de oudste academische instellingen gespecialiseerd in het recht van de Europese Unie en het Europees Verdrag inzake de Rechten van de Mens. Het werd opgericht in 1957, hetzelfde jaar als de Europese Economische Gemeenschap zelf.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Promotores: Prof.dr. C.A.M.J.J. van den Hondel, Prof.dr. V. Meyer (Technische Universität Berlin)