Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

The Joan Van der Waals colloquium is an ongoing bi-weekly lecture series.

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For his dissertation, Joost Akkermans searched for areas of improvement for delicate fetal laser surgery with Twin Transfusion Syndrome (TTS). This syndrome occurs in the Netherlands 60 to 70 times a year among single-egg twins sharing one placenta. Treatment is possible, but not without risk. Inaugural…

Maurijn van der Zee, at the IBL since 2010, investigates how genetic changes in developmental programs lead to new animal forms in evolution, using insects as model system. His field of research is called evolutionary developmental biology. Currently, he is working on the success and diversity of the…

In the programme NWO Open Competition Domain Science - GROOT, twenty new consortia will start a large research project. This boost of more than 47 million euros will make new research possible in the science domain. Among the winners is the Nanoscale Regulators of Photosynthesis consortium in which…

Researchers Indu Khatri, Frank Staal and Jacques van Dongen from Leiden University Medical Center (LUMC) have published a perspective article in Frontiers in Immunology about coronavirus and its characteristic ‘spike protein.’ They predict which antibodies would provide the best protection against the…

Researchers from Leiden University will develop a new approach to study the biomarkers of Alzeimer’s disease. This approach focusses on the molecular messengers of the cells. The project, led by Thomas Hankemeier and coordinated by Yuliya Shakalisava (Leiden Academic Centre for Drug Research, LACDR),…

Migration and crime are in the spotlight in society. Within the Institute for Criminal Law and Criminology, research in this area has strongly developed in recent years. The concept of Crimmigration is central to this.

The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…

Since the end of the nineteenth century Arabic book designers have influenced the social and cultural situation in the Middle East with their work. Huda Smitshuijzen Abi-Farès has written the first global overview of this neglected field of science. PhD defence 10 January.

Physicist Jelmer Renema will spend two years conducting research at Oxford University in Great Britain funded by a Rubicon grant from NWO.

On Thursday November 15th, Leiden University organizes its Physics & Astronomy Ladies' Day for female high school students. To mark this festive day, we put the spotlight on five female researchers, who talk about their experiences working in science.

A team of laboratory astrophysicists from Leiden University managed to make glycerol under conditions comparable to those in dark interstellar clouds. They allowed carbon monoxide ice to react with hydrogen atoms at minus 250 degrees Celsius. The researchers publish their findings in the Astrophysical…

Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…

In a publication in Science, Noam Zelcer from the Division of Biopharmaceutics describes a previously unrecognized pathway to regulate LDL-cholesterol levels. He is also able to modulate this pathway. This opens the possibility for complementing and improving the efficacy of statins: A class of drugs…

It's pretty hard to spot a single 5 nanometer particle. Leiden physicists pulled it off by turning a 120 nm gold rod into a detector.

Professor of Pharmacochemistry Ad IJzerman has won the Nauta Award for his years of research into signal processing proteins that are interesting for the development of new medications: G protein coupled receptors. The prize is awarded every two years for services to pharmacochemistry and chemical b…

Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.

A consortium of international researchers comes with a unique solution to the energy problem. By mimicking photosynthesis, they aim to produce sustainable fuels out of sunlight, water, and CO2. Their secret? ‘Soap bubbles’, says Leiden chemist Sylvestre Bonnet, who is part of the consortium.

The Leiden Academic Centre for Drug Research (LACDR) received no less than three awards during the Figon Dutch Medicine Days. Bas Goulooze won the PhD Prize for best PhD candidate, Natalia Ortiz Zacarías and Huub Sijben both received a poster prize. ‘Scientists must be able to communicate their research…

On Tuesday 4 September, Martina Vijver delivered the scientific lecture during the academic opening of the Faculty of Science. Martina is professor in Ecotoxicology at CML and would like to have collaborations with colleagues from the Leiden Centre of Data Science. We had a brief interview with her.

How can a single origami crease pattern be folded into two precisely defined target shapes? Researchers at AMOLF and Leiden University have created an ‘alphabet’ of 140 origami ‘puzzle pieces’ that allows them to do just that, as described today in Nature Physics. This discovery could help in the construction…

A certain type of oil droplets changes shape when cooled and shrunk: from spherical through icosahedral to flat hexagonal. Two competing theories couldn't fully explain this, but now, a Physical Review Letter by Ireth García-Aguilar and Luca Giomi solves the mystery.

Every year, an NWO PhD in the Humanities grant is awarded to a prospective PhD candidate at the Faculty of Archaeology. This year, the grant went to Maia Casna, enabling her to study respiratory disease in the past. ‘My hypothesis is that the rapid formation of cities in the medieval Netherlands, must…

Spitting cobra venom composition has been influenced by defensive behaviour according to an international research team. This may have originated from the arrival of human ancestors. Students at the Institute of Biology Leiden made an important contribution to the study. Publication in Science on 22…

The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…

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For the first time more than half century, one of oldest telescopes at Leiden Observatory is getting a major improvement.

Two courses on Central Asia will be offered within the Leiden Central Asia Initiative, funded by the research profile area Asian Modernities and Traditions. 'History of Central Asia & Afghanistan' will be open to BA students of Middle Eastern Studies and 'Material Culture, Memory and Commemoration along…

We increasingly look at international consortia to come up with scientific and technological advances that are needed to address global challenges in areas such as health, the environment and clean energy. However, organising these consortia involves unique challenges. To identify these challenges,…

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Congres/symposium

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Festival, Middle Eastern Culture Market 2019

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Kunst en Cultuur, LUCIS exhibition opening | Islam in Central Asia

A vaccine based on sugar coats does have the potential to combat a multi-resistant staphylococcus. That is what Jeroen Codée and his colleagues from Utrecht state in Nature. In doing so, they are contradicting the earlier conclusions of German colleagues.

Photosynthesis is the origin of life on earth, but it is a phenomenon that is still barely understood. Take, for example, the extremely efficient mechanism of electron transport. Leiden researchers demonstrate for the first time where one particular cause of this might be found.

Those pesky raindrops that get you wet on your way to work, are formed high up in the sky from clouds of water vapour. The process of nucleation describes the way this happens. Edgar Blokhuis of the Leiden Institute of Chemistry developed a theory to describe this transition more precisely. Chemists…

Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…

On Friday October 25th the fourth annual Jan Reedijk Symposium will be held. The main lectures of the day will be

Alireza Mashaghi from the Leiden Academic Centre for Drug Research (LACDR) will use state-of-the-art technology to investigate proteins that play a role in muscular dystrophy. His goal is to provide new insights for designing novel therapeutic strategies in the future. To accomplish this, Mashaghi receives…