285 zoekresultaten voor “membrane fusion” in de Publieke website
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Chemical approaches to control the in vivo behavior of nanomedicines
Lezing, Van Leeuwenhoek Lecture on BioScience
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ERC Consolidator Grant for Leiden
Leiden University professor of Science-Based Business Simcha Jong Kon Chin has been awarded an ERC Consolidator Grant.
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Daniela Kraft wins Biophysical Journal Paper of the Year Award
The editors of Biophysical Journal have selected a publication from Daniela Kraft’s group as the Paper of the Year 2017. The award recognizes an outstanding contribution by a young investigator.
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Chromatin organisation & dynamics
The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
- Publication highlights
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Reedijk Symposium 2015 - Guest Lecturers: Prof. Bas de Bruin & Prof. Dame Carol Robinson
On Friday October 30th 2015 the sixth annual Jan Reedijk Symposium will be held. The main lectures of the day will be
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This Week’s Discoveries | 20 september 2016
Lezing
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Chris Smiet wins Christiaan Huygens prize
Christopher Berg Smiet, who defended his thesis at LION with Dirk Bouwmeester, won the Christiaan Huygens prize for his thesis '‘Knots in Plasma’. On 7 October, he received a certificate, a bronze statuette and ten thousand euros.
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Postdoctoral researcher in the field of supramolecular chemistry
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Research
PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…
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PhD Theses
A full overview of CASC PhD theses.
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Biophysical Organic Chemistry
The long term goal of the Biophysical Organic Chemistry/SSNMR group, headed by Prof. Huub de Groot, is to reach an understanding of structure, dynamics and functional mechanisms of membrane proteins and self-organized biological assemblies and to translate this knowledge into new concepts for nano-devices,…
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Sexuality in the consulting room embarrasses oncologists
Cancer treatments often have an impact on people’s sexual health, but doctors and nurses do not discuss topics such as sexuality and intimacy with patients as a matter of course. This is what Esmée Krouwel, a physician-researcher at Leiden University Medical Center (LUMC), has discovered. With her research…
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How insects conquered land
IBL-researchers revealed in a new study that insects are successful on land because their eggs became protected against desiccation. An extraembryonic membrane in the egg, the serosa, helped insects to make the transition from water to land.
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PhD thesis award for Biologist Chris Jacobs
Chris Jacobs, former PhD-student of the IBL, received the national “Dissertation Award” for best PhD thesis of the year on insects. The award was handed out last Friday, the 18th of December, by Professor Matty Berg, president of the Dutch Entomological Society.
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Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
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Real-time solid-state NMR spectroscopy inside living cells
Researchers from the Leiden Institute of Chemistry show proof of principle that live-cell structural changes and metabolic processes can be followed in real time with NMR spectroscopy. They performed their study on photosynthetic green algae that are metabolically flexible and can sustain energy generation…
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New paradigm for visual recognition
Leiden University computer scientists Yu Liu, Yanming Guo and Michael Lew are a step closer to their ultimate goal: search engines with visual recognition. Their publication of a new algorithm for fusing multi-scale deep learning representations has been received with great enthusiasm. No other algorithm…
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Miraculous mechanism allows plant cells to directionally distribute the growth hormone auxin
Leiden and Austrian researchers have succeeded in further uncovering how a plant cell passes on the growth hormone auxin in a directional manner to the next cell. Three proteins that cling together in a bunch appear to be essential for this important transport process. ‘This discovery solves a crucial…
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Blog post: The nose of this wormy-shaped bacterium has a surprising symmetry
For the first time ever, Leiden biologists have found that the ‘nose’ of spirochetes – worm-shaped bacteria – have a two-fold symmetry. A remarkable discovery, as the ‘nose’ of every other bacterium has been found to have a six-fold symmetry. First author Alise Muok wrote a popular blog about the findings…
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“Principles of Plant-Microbe Interactions”
Emeritus Professor Ben Lugtenberg edited a book on “Principles of Plant-Microbe Interactions” together with Paul Hooykaas, Eddy van der Meijden and Jos Raaijmakers, all from the IBL.
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Professor Ben Lugtenberg received ‘The Arima Award for Applied Microbiology’
Emeritus Professor Ben Lugtenberg received ‘The Arima Award for Applied Microbiology’ from the IUMS (International Union of Microbial Societies) for his life-time contributions to this field.
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Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease
How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?
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Glucocorticoids in zebrafish
A novel in vivo model system for studies on glucocorticoid resistance
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Sustainability Guide & Energy Saving
We would like to present to you a simple guidebook about living a sustainable life as a student in the cities of Leiden and The Hague. Whether you are a first-year student still trying to find your way around or already doing your masters – students wanting to explore more sustainable options and save…
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From Data to insight
Social science research helps us understand human behaviour and social structures. These are determined by various factors, which makes the research complex and increases the likelihood of drawing the wrong conclusions. The choice of research method and analysis is therefore extremely important. It…
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Travelling through the body with graphene
For the first time researchers have succeeded in placing a layer of graphene on top of a stable fatty lipid monolayer. Surrounded by a protective shell of lipids, graphene could enter the body and function as a versatile sensor. The results are the first step towards such a shell, and have been published…
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Four bold Faculty of Science researchers receive NWO XS grants
Four scientists from the Faculty of Science will receive a grant of up to 50,000 euros in the Open Competition Domain Science - XS from science financier NWO. This category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.…
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Collaboration starts quest for new antibiotics through NWO fund
Identifying novel antibiotic compounds to tackle antibiotic-resistant bacteria. Researchers from Leiden University and VU Amsterdam will unite through a project now funded by NWO’s Open Technology Programme (OTP), which awarded the collaboration nearly one million euros.
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New insight into tuberculosis infection
Michiel van der Vaart with a team from Leiden University and the LUMC, led by IBL-researcher Annemarie Meijer, discovered that DRAM1 is a protein that regulates anti-bacterial autophagy, a defense mechanism against infections such as tuberculosis.
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Postdoctoral researcher in structural biology of glycan-modifying enzymes
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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PhD candidate , Lysosomal delivery of intracellular pathogens
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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Theory
Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…
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Mimetas receives 5.2 million dollar investment for organ-on-a-chip
Venture capital investors Zeeuws Investerings Fonds and Participatiemaatschapij Oost Nederland have joined forces with national and regional partners to fund development and sales of MIMETAS’ unique 3D disease- and tissue modelling technologies.
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Dr. Elizabeth de Lange awarded as AAPS Fellow
The American Association of Pharmaceutical Scientists (AAPS) has been pleased to announce Dr. Elizabeth de Lange as a recipient of the 2013 AAPS Fellows Award at the 2013 AAPS Annual Meeting and Exposition in San Antonio.
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Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.
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Holland Research School of Molecular Chemistry awards PhD project to David Klein
Leiden based chemistry student and chess grandmaster proposes molecular system for development of artificial leaf
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New insights on graphene
Graphene floating on water does not repel water, as many researchers believe, but rather attracts it. This has been demonstrated by chemists Liubov Belyaeva and Pauline van Deursen and their supervisor Grégory F. Schneider. Publication in Advanced Materials.
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Detecting diseases with molecules in the body
Is it possible to diagnose diseases using molecular switches? The new international consortium LogicLab will address this question. Leiden chemist Sylvestre Bonnet and Leiden pharmacologist Thomas Hankemeier are involved in the project. LogicLab will run for four years and will receive over 3.5 million…
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Communicating Communities
Unravelling networks of human mobility and exchange of goods and ideas from a pre-colonial, pan-Caribbean perspective
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Research scientific programmer, Automated machine learning for spatio-temporal Earth Observation datasets
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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Career prospects
As a graduate of Linguistics (MA), you will have developed unique skills relevant to a career in academia, teaching, writing and communications, as well as a range of employment opportunities where a critical, curious, and academically-trained mind is essential.
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Record distance for alternative super current
Electrons that spin synchronously around their axis, turn out to stay superconducting across large distances within magnetic chromium dioxide. Electric current from these electrons can flip small magnets, and its superconducting version could form the basis for a hard drive without energy loss. Publication…
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Leiden biologist receives National Zoology Award
Maurijn van der Zee, evolutionary biologist at the IBL, received the National Zoology Award for his research on the evolutionary success of the insects. The award was handed out last Saturday, the 17th of December, by Professor Jan Kammenga, chairman of the Royal Dutch Zoological society.
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Vidi Grant for Stefan Semrau: how does bioelectricity shape embryonic development?
Leiden biophysicist Stefan Semrau was granted an NWO Vidi earlier this month. He will use the grant to study the role of electricity in embryonic development and tissue regeneration.
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Tom Lubensky appointed 2018 Lorentz Professor
Coming spring, Professor Tom Lubensky from the University of Pennsylvania will be the 64th Lorentz Professor at the department of Theoretical Physics. He is a pioneer in the field of theoretical soft matter physics and winner of the prestigious Buckley Condensed Matter Prize. During his stay in Leiden…
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Awards and prizes 2020
An overview of awards and prizes granted to our staff and students in 2020, as well as special appointments at Leiden University and other institutions.
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Assistant/Associate Professor (tenure track) / Full Professor
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)