Promotores: A.H. Meijer, H.P. Spaink

Animal Sciences’ contributions to the Host-Microbe Interactions research theme focus on the interaction of animal hosts with pathogenic microbes but also the beneficial role of the gut microbiome.

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

How does the endocannabinoid system in the zebrafish function at the molecular and phenotypic levels and how is it linked to the stress axis?

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Unraveling the immune-suppressive actions of drugs like prednisone.

In the theme Animal sciences and health research, we work with different species of animals to learn more about fundamental biological processes.

Promotor: G.R. de Snoo Co-promotor: C.J.M. Musters

Promotor: Huub de Groot, Co-promotor: Francesco Buda

Does a mid-season fire impact invertebrate populations?

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

We examine how soil-derived legacy effects of plants structure natural ecosystems, determine aboveground plant insect interactions, and how we can use soil legacy effects to restore degraded ecosystems.

The lipid matrix of the skin's stratum corneum plays a key role in the barrier function, which protects the body from desiccation. The lipids that make up this matrix consist of ceramides, cholesterol, and free fatty acids, and can form two coexisting crystalline lamellar phases: the long periodicity…

Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.

How can Staphylococcus aureus bacteria subvert the host immune system?

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Lezing

The production, use, and exchange of bodily ornaments through the lenses of the microscope

Promotor: J. Schaye

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

This project develops a scientific method to extract clinically relevant new information from patient forum websites that discuss patient experiences concerning e.g. medication, nutrition, co-morbidities, genetic factors etc.

Promotor: H.V.J. Linnartz

How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?

Paul van Enckevort defended his thesis on 3 June 2020.

Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Bicarbonate buffer is largely found in nature due to its ability to regulate pH variations around neutral values. As the pH changes, so does the speciation of the buffer.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

Atherosclerosis, in particular rupture of atherosclerotic plaques, is the underlying cause of most heart attacks or strokes and is the leading cause of death worldwide.

Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?

My work focuses on a class of astronomical objects called protoplanetary disks.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Does roadside management in the mid-west USA increase invertebrate diversity similar to practices in Europe?

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Kohei Suzuki, Assistant Professor at Institute of Public Administration, researched, together with two other authors, whether public managers with private sector experience have more core managerial values.

This project aims to open up the pre-Islamic linguistic history of Arabia through the systematic study of the Thamudic inscriptions within a digital humanities framework.

The abundance of images in our everyday lives-and the speed at which they are consumed-seems to have left us unable to critique them. To rectify this situation, artists such as Daniel Richter, Jaune Quick-to-See Smith, and Artur Zmijewski have demonstrated that painting is brilliantly equipped to produce…

In this study, Tessa Dool and Thijs Bosker estimate the microplastic uptake of two odontocetes in the Mediterranean Sea and the Norteast Atlantic.

New funding allows IBL-researcher Herman Spaink to purchase a measurement device for more studies on human diseases such as cancer and tuberculosis using zebrafish as the model system.

To what extent is sound a stressor to fish? And are behavioural and physiological phenotypes equally sensitive to disturbance by noise pollution?

Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?

Key publications of the Systems Pharmacology group

How has early development in R. ocellatus been modified as a result of its parasitic embryonic lifestyle?

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.