Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Promotor: G.R. de Snoo Co-promotor: C.J.M. Musters

Promotor: Prof.dr. H.J.M. de Groot, Co-promotor: Francesco Buda

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

Promotor: E. Gittenberger, Co-promotores: B.W. Hoeksema; L.P. van Ofwegen

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

Promotie

Onderzoekers van LIACS werken aan het bedenken van de computers van morgen die de ruggengraat zullen vormen van de Cloud en Edge computing paradigma’s en ‘the Internet of Things’. In dit verband zijn we betrokken bij onderzoek en ontwikkeling van high performance computing systemen, embedded & real-time…

What would be the environmental performance of the Carbon4PUR technology at industrial scale in the future?

Developing methodes to understand the evolution of patches in natural ecosystems

BioSolar Cells is a five-year research project in which ten knowledge institutions and 45 private industries work together.

Wereldwijde uitdagingen aanpakken via internationale wetenschappelijke consortia

In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.

Rachel Schats is Assistant Professor in Human Osteoarchaeology in the Faculty of Archaeology, Leiden University.

Promotie

Geesteswetenschappen, Centre for Linguistics

The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

Promotor: Prof.dr. G.R. de Snoo

Promotores: H. Schiessel, G.T. Barkema

What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?

This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.

Does a high quality prairie restoration in an urban/agricultural landscape provide invertebrates necessary for a sustainable ecosystem?

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

We find ourselves in an era of transition, not just towards a more computing- and data-driven society but also away from unsustainable fossil fuels as an energy source.

How the global distribution of vegetation stands dominated by arbuscular and ectomycorrhizal plants relate to principle aspects of belowground carbon accumulation processes?

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

To study how planetary systems come into existence we study much younger systems still in formation.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Promotores: J. Zaanen, A. Parnachev

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.

Promotor: Prof.dr. A. Achucarro

Promotor: Prof.dr. S. Portegies Zwart

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…

What invertebrates live in the fields and edges? Do the populations change with landscape complexity?

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).

Promotor: M.A.G.J. Orrit

Promotores: P.G.L. Klinkhamer, P.M. Brakefield, Co-Promotor: M. Bruinsma

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.