Promotor: M.L. van Hecke, Co-Promotor: B.P. Tighe

Promotor: M.L. van Hecke

What would be the environmental performance of the Carbon4PUR technology at industrial scale in the future?

What are the mechanics of soft materials (e.g. foam, sand)?

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Macrophages and atherosclerotic lesions The infiltration of monocytes in the arterial wall, their differentiation to macrophages, and the subsequent accumulation of cholesterol in these macrophages initiate the process of atherosclerosis. We study the importance of specific genes in macrophages for…

Vitelli

The Physics and Biological and Soft Matter master's specialisation is one of the two programmes that Leiden University offers in experimental physics. This programme mainly focuses on Biological Physics and Soft Matters Physics.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

Selected publications of the Cardiovascular and Metabolic Therapeutics group.

Leiden University offers ambitious students a great environment in which to reach their potential.

It might be possible to prevent atherosclerosis by changing the appearance of macrophages, cells of the immune system that for example digest foreign substances. In her PhD dissertation, Baoyan Ren examined several ways to do so.

Between foraging and farming: an extended broad spectrum of papers presented to Leendert Louwe Kooijmans.

The Biological- and Soft-Matter Physics Master specialisation is one of the two programmes Leiden offers in experimental Physics. The programme can to a high degree be tailored to individual needs and interests.

Not many scientists can claim to have received funding from NWO to blow bubbles and play with sand, but Martin van Hecke definitely can. Van Hecke, Professor of the Organisation of Disordered Matter, delivered his inaugural lecture on Friday 4 September, under the enigmatic title of: ‘Bellen, bollen,…

The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…

Coming spring, Professor Tom Lubensky from the University of Pennsylvania will be the 64th Lorentz Professor at the department of Theoretical Physics. He is a pioneer in the field of theoretical soft matter physics and winner of the prestigious Buckley Condensed Matter Prize. During his stay in Leiden…

Vanessa Frodermann, a PhD student at the Biopharmaceutical department of the Leiden Academic Centre for Drug Research, has discovered that arteriosclerosis could be inhibited by cellular therapy. Arteriosclerosis is one of the leading causes of the development of cardiovascular disease. Her PhD defence…

This year, NWO has awarded a Veni subsidy to 143 young researchers who have recently obtained their PhD. 17 of these researchers are at Leiden University and one works at the LUMC. The successful applicants will each receive 250,000 euro to develop their ideas and carry out research over a period of…

Silver jewellery, sculptures made of cork and intriguing photos of psychiatrists' treatment rooms. Staff at Leiden University exhibit their artworks in the Old Library. The summer exhibition can be viewed until 12 August.

Art and science: are they polar opposites? The theme of this year’s Sculptures in Leiden open air exhibition is ‘life sciences’. It has resulted in many intriguing sculptures, including one that is especially endearing.

Anneloes van Iwaarden works part-time as a communications manager at the Centre for Linguistics (LUCL). She grew up in England, Switzerland and the Netherlands, where she eventually studied international relations. But her passion was always writing.

Materials that are built up from individual granules exhibit a special phenomenon called ‘jamming’. With research into the nature of this phenomenon, a team of scientists led by Leiden physicist Prof. Martin van Hecke has made it to the cover of the prominent journal Physical Review Letters. ‘Jammed…

Lezing

Festival

Recent publications