Promotores: K.J. Batenburg, B. Koren

In this thesis we study products of linear error correcting codes.

The results of the investigations by citizens are used in an innovative research project that investigates the potential of machine learning and automated detection in archaeology.

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On 8 January 2020, Jelmer Brouwer defended his thesis 'Detection, detention, deportation'. The doctoral research was supervised by Prof. J.P. van der Leun and Prof. M.A.H. van der Woude.

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

In this project we develop algorithms to automatically detect a particular type of archaeological sites in satellite images of the Alps.

Promotor: E.R. Eliel, Co-Promotor: M.J.A. de Dood

Promotor: Prof. dr. I. Snellen, Co-Promotor: Dr. M. Kenworthy

Our group explores the larger domain of quantum measurement. In particular we investigate two themes that are closely connected: The detection of specially prepared quantum states of light and understanding and characterizing quantum photon detectors.

Promotor: E. Bouwman Co-Promotor: S. Bonnet

On the 10th of November, Martin Kroon successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Martin on this achievement!

So far it has been impossible to compare large sets of syntactic constructions in large sets of languages systematically and automatically. The online availability of parallel text corpora and software tools to align, enrich, search and analyse them has the potential to make automatic massive systematic…

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

This advanced summer programme, organised together with the International Centre for Counter-Terrorism – The Hague (ICCT), provides insight into the opportunities and challenges of various approaches to prevent, detect and respond to violent extremism.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Generally the data from remote sensing surveys - the scanning of the earth by satellite or aircraft in order to obtain information about it - is screened manually in archaeology. However, constant monitoring of the earth's surface causes a huge influx of data of high complexity and high quality. To…

How do nanoparticles bioaccumulate and biodistribute in organisms?

It’s not a regular occurrence at Leiden University: two professors giving their inaugural lecture on the same day. Berna Güroğlu and Ellen de Bruijn specialise in related disciplines: they both research the influence of social context on processes in the brain – Güroğlu in adolescents and De Bruijn…

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

Metamaterials have properties that depend on their shape and architecture. Researchers at AMOLF, Leiden University and Tel Aviv University have found a new way of designing these metamaterials and their properties by deliberately incorporating small errors. They publish their results today in Nature…

The manual analysis of remotely-sensed data is a widespread practice in local and regional scale archaeological research, as well as heritage management.

Ariane Briegel wants to use bacteria to detect cancer at an early stage. Together with postdoc Alise Muok, she is developing a method to quickly and cheaply test the urine of patients for the presence of suspicious molecules. They receive a grant of approximately 150,000 euros from the Dutch Cancer…

For his PhD project, computer scientist Manolis Fragkiadakis is developing a tool that can compare videos of sign language corpora. This would make it possible to detect differences between sign languages and prevent translation errors. Ultimately, the tool could be used to compare sign languages from…

In a recent TEDx Flanders event “Statistical Errors in Court”, Statistical Scientist Richard Gill speaks about the case of Lucia de Berk, a nurse found guilty of several murders based largely on statistics.

When new features are being written into software code, errors can easily be made. This causes bugs, which leads to software appearing later and being more expensive. Michiel Helvensteijn, a PhD student from CWI and the Leiden Institute of Advanced Computer Science, studied how to prevent these kinds…

Leiden and Jülich researchers discovered an elegant and simple approach to improve the sensitivity of graphene biosensors. These so-called ‘next generation graphene electronic biochemical sensor devices’ are able to detect very low amounts of HIV DNA thanks to their very low electronic noise.

It's pretty hard to spot a single 5 nanometer particle. Leiden physicists pulled it off by turning a 120 nm gold rod into a detector.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

NWO honoured Leiden psychologist Jeffrey Durieux with a Research Talent Grant for early dementia detection by identifying differences in resting-state networks.

Over the past decades within the European Union (EU), economic proliferation and globalisation have resulted in an increase in transboundary waste transportation. Although waste trading can often have positive economic and environmental impacts by repurposing natural resources within industrial sectors,…

With the emergence of social media platforms such as Twitter, Facebook and Instagram, it’s easier than ever to share information. Including disinformation. During his PhD computer scientist Xueqin Chen developed a new way to recognise fake news and predict how messages spread within online social networks…

The James Webb Space Telescope has found evidence of carbon dioxide (CO₂) in the atmosphere of a giant planet 700 light years away. This result provides insight into the composition and formation of this gas giant and shows what James Webb is capable of. The research by the international group of astronomers,…

Physicists, including Leiden researcher, Sanli Faes, have devised a new technique for studying processes at microscale rapidly and extremely precisely. This new method will make it easier to develop antiviral medication. And it doesn’t stop there. Publication in ACS Nano.

Is it possible to diagnose diseases using molecular switches? The new international consortium LogicLab will address this question. Leiden chemist Sylvestre Bonnet and Leiden pharmacologist Thomas Hankemeier are involved in the project. LogicLab will run for four years and will receive over 3.5 million…

Optical detection of a single electron using a single molecule has never been done. Leiden physicist Michel Orrit and his team have now identified a molecule that is sensitive enough to detect an electron at a distance of hundreds of nanometers. The results are published as a cover article in ChemPh…

Empathic or anxious mistakes? A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

For many years, scientists have observed a correlation between Alzheimer’s disease and a surplus of iron in the brain. However, a causal link between the two has not been proven yet. We lack knowledge concerning the specific form of iron that is involved in the development of neurodegenerative diseases.…

Starting four years ago, the same privacy laws apply throughout the European Union: the General Data Protection Regulation (GDPR). The law also affects our work at the university. As a refresher, we spoke with Privacy Officer Max van Arnhem about privacy in the workplace and what to do if something…

Leiden physicists have managed to detect a single molecule called dibenzoterrylene in a new crystal, and found that it is a candidate component for a quantum network. Future quantum computers will need such a network to work together while maintaining their advantages. Publication in ChemPhysChem jo…

Promotor: A.W. van der Vaart

Astronomers from Leiden Observatory have developed a new method to find distant quasars and better distinguish them from other objects that look like them, using machine learning techniques. The research result has been accepted for publication in the journal Astronomy & Astrophysics. It is the last…

By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…