Promotores: G.W. Canters, T.J. Aartsma

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Electron microscopy has become an extremely important techniquein a wide variety of elds.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Het doel van deze faciliteit is om het biomedisch onderzoek te versnellen door toegang te bieden tot geavanceerde licht- en elektronenmicroscopie en door het delen van expertise over monstervoorbereiding, beeldvormingsmodaliteiten, gegevensopslag en beeldanalyse.

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

The dissertation describes TEM experiments on heterogeneous catalysts.

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Promotor: J. Zaanen, Co-Promotor: V. Juricic

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Promotor: T.J. Aartsma, Co-promotor: R.N. Frese

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

Promotor: Prof.dr. M. Ubbink

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

Promotor: W. Jaffe, Co-promotor: K. Meisenheimer

Aim: To develop and enable application of a practical, flexible, user-friendly platform to provide the scientific community with a tool to generate land surface products and its associated uncertainties and exploit these for data-intensive science.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

Promotor: Prof.dr. E.F. van Dishoeck

Biodiversity enables ecosystems to thrive through the synergy of functional differences among organisms. While human well-being strongly depends on biodiversity-driven ecosystem services, human actions are also at the root of current unprecedented biodiversity declines.

Promotor: H.J.M. de Groot

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.

This thesis discusses the physical and chemical processes than influence the composition of forming planets.

What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?