718 zoekresultaten voor “chromatin architecture” in de Publieke website
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Laura PlezierFaculteit der Geesteswetenschappen
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The idea of the primitive hut
Subproject of
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NWO ECHO grant for research on fickle RNA production
Genes are active sometimes, and other times they remain dormant for a while. Leiden physicist John van Noort receives an NWO ECHO grant to find out how this happens.
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Dissertation: existence and development of the European security architecture
On Thursday 15 April, Sabine Mengelberg, associate professor at the Faculty of Military Sciences of the Netherlands Defence Academy (NLDA), will defend her thesis on changes in European security architecture. Permanent Change? The Paths of Change of the European Security Organizations is the title of…
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DNA folded in compliant helix
In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Guy LivingstonFaculteit der Geesteswetenschappen
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Elizabeth den HartogFaculteit der Geesteswetenschappen
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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DNA repair in chromatin: the cancer connection
Lezing
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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Helmut Schiessel Group (Theoretical Physics of Life Processes)
The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.
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Get to know Roberta D'Alessandro and discover the architecture of language
How does language work and how do we learn a language? The more we know about language, the better we can understand how people interpret the world in words. Roberta D'Alessandro carries out research on the architecture of language. There is now a dossier about her work online.
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Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
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Antoinette HuijbersFaculteit Archeologie
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Roos StolkerFaculteit Governance and Global Affairs
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Valentina AzzaràFaculteit Archeologie
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Hans TheunissenFaculteit der Geesteswetenschappen
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Lithic Technology, Social Agency and Cultural Interaction in the Bronze Age Aegean
LiTechAe: Percussive stone tools related to stone masonry techniques seen through experimentation and use-wear analysis.
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Alexander GeurdsFaculteit Archeologie
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Packaging and accessing DNA molecules
Our DNA molecules are packaged by proteins in compact structures. The aim of this project is to understand how modern gene editing techniques nevertheless get access to their target in the DNA.
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Human genetics, in particular chromatin and DNA repair
Oratie
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Elevated minds: The Sublime in the public arts in 17th-century Paris and Amsterdam
The aim of this project is to study the influence of Longinus’s treatise ‘On the sublime’ on practice and theory of architecture and theatre in seventeenth-century Paris and Amsterdam.
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Marie-leen Ryckaert
Faculteit Governance and Global Affairs
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Diederik SmitFaculteit der Geesteswetenschappen
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Promotie
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Modifying the modifier: Discovering mechanisms of SMCHD1 mediated chromatin repression
Promotie
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The Role of Linker DNA in Chromatin Fibers
Promotie
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Collaborations
Find out more about our national and international research collaborations.
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Exhibition: Silk Road Cities
Kunst en Cultuur, LUCIS exhibition opening | Islam in Central Asia
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Chromatin modifiers in DNA repair and human disease
Promotie
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SETinSTONE
A retrospective impact assessment of human and environmental resource usage in Late Bronze Age Mycenaean Monumental Architecture, Greece
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Ann BrysbaertFaculteit Archeologie
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Alexander DencherFaculteit der Geesteswetenschappen
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Chemical Biology Lecture: PARP activation upon DNA damage induces chromatin dynamics
Lezing
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Publications
Relevant publications of the CIGR participants.
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Our approach
Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:
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Chemical Biology Lecture: The mechanism of ATP-dependent chromatin remodeling
Lezing
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Lyndsey Housden
Lyndsey Housden teaches in the Interactive/Media/Design department at the Royal Academy of Art (KABK), The Hague. She is a researcher and artist, working with interactive and haptic installations, spatial design and interdisciplinary projects for exhibitions, theatre, and festivals.
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Cosmological interpretation of architecture
Promotie
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Architectural terracottas from Akragas
Promotie
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Social Technology of (mudbrick) Architecture
Lezing
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Exposition MEMORY: Architecture of Belonging
Promotie, Artistic work associated with Public Defense
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the equilibrium between ERa-activation, epigenetic alterations and chromatin integrity
Promotie
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
Promotie
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Responding to environmental cues: The adaptive qualities of chromatin compaction proteins
Promotie
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Portable Antiquities. Two lectures on historical building fragments from ancient times
Alumni-activiteit, Lecture
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Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
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The Salm story: the forgotten architects of the Netherlands
Music venue Paradiso, the Keizersgracht Church and the Artis Zoo’s aquarium: these buildings all owe their design to architects Gerlof Bartholomeus Salm and Abraham Salm. Remco van der Kuijp researched the place of father and son in architectural history. PhD defence on 25 March.
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A molecular journey : tales of sublimating ices from hot cores to comets
The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.