306 zoekresultaten voor “cancer progression” in de Publieke website
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Lioe-Fee de Geus-OeiFaculteit Geneeskunde
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Photodynamic therapy-based combinations with immunotherapy in colon cancer treatment
Promotie
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Modulating the behaviour of pancreatic tumour cells
Promotores: Prof.dr. M.K. Richardson, Prof.dr. H.P. Spaink. Co-promotor: C.P. Bagowski
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar
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Dwaipayan Banerjee - Enduring Cancer
Lezing, Online webinar
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Essentieel eiwit voor uitzaaiing kanker gevonden
Een essentieel eiwit dat onze hartslag reguleert blijkt ook belangrijk te zijn voor kankercellen. De ontdekking zou kunnen leiden tot nieuwe behandelingen tegen uitzaaiing. Publicatie in Science Signaling op 4 april.
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Cancer drug target discovery
Oratie
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Biomarkers in colorectal cancer
Promotie
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Cancer detection & visualization
Promotie
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Brachytherapy for rectal cancer
Promotie
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Locally advanced rectal cancer
Promotie
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Radiotherapy for endometrial cancer
Promotie
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Multilayer cancer glycomis
Promotie
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Improving colorectal cancer care
Promotie
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Epigenetic alterations in the predisposition to and progression of melanoma
Promotie
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Risk factors of Chronic Kidney Disease Progression: Dutch Cohort studies
Promotie
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Assuring quality in cancer care
Promotie
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Light and nanoparticles against cancer
Lezing, This Week's Discoveries
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Stromal immunobiology in gastrointestinal cancer
Promotie
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Tumoren trekken bloedvaten aan met ‘afstandsbediening’
Onderzoekers van de Universiteit Leiden hebben aangetoond dat tumoren op een mechanische manier bloedvaten kunnen aantrekken, waardoor ze kunnen groeien. Het team publiceerde deze ontdekking op 2 maart in Nature Scientific Reports.
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Videocollege: Wat is kanker precies?
Kanker is nog altijd een van de meest voorkomende ziektes in de wereld. In een video van de Universiteit van Nederland legt Noel de Miranda (kankerimmunologie, LUMC) uit wat kanker is en vertelt over zijn onderzoek naar nieuwe behandelingen.
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Killing cancer cells with metals and light
Lezing
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DNA repair in chromatin: the cancer connection
Lezing
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Ruim 700.000 euro voor de strijd tegen agressieve borstkanker
Eiwitten remmen die een rol spelen bij de groei van agressieve kankercellen, dat is het plan van professor Bob van de Water en zijn team. Zij ontvangen hiervoor ruim 700.000 euro van KWF Kankerbestrijding. Onderzoeker Maaike Vreeswijk en patholoog Danielle Cohen zijn aangesloten vanuit het LUMC.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Tailored treatment for colon and rectal cancer
Promotie
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Identification of regulators of cancer - immune interactions
Promotie
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Surgical outcome of colorectal cancer screening
Promotie
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Frailty and outcomes in older cancer patients
Promotie
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Monitoring Outcomes In Colorectal Cancer Surgery
Promotie
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The use of light in cancer immunotherapy
Promotie
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Tumor-immune interactions in colorectal cancer
Promotie
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The path to individualised breast cancer screening
Promotie
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Cancer vaccine strategies to improve immunotherapy
Promotie
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Therapeutic targeting of immune-escaped cancers
Promotie
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Formulation of Peptide-Based Cancer Vaccines
Promotie
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Joining forces in endocrine cancer genetics
Promotie
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Immuunsysteem speelt dubbele rol bij borstkanker
Het immuunsysteem speelt een paradoxale rol bij de uitzaaiing van borstkanker. Dat ontdekte Kelly Kersten in haar promotieonderzoek. Sommige immuuncellen dragen bij aan uitzaaiingen, terwijl andere cellen kunnen worden aangezet om chemotherapie effectiever te maken. Promotie op 7 februari.
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Genetic and lifestyle factors in breast cancer prognostication
Promotie
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Safeguarding ovarian tissue autotransplantation in cancer patients
Promotie
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Vulvar cancer; pathogenesis, molecular genetics and treatment
Promotie