The research in the Biosyn group is focused on the design, synthesis and function of the four major types of biomolecules: nucleic acids, carbohydrates, peptides and lipids and hybrid structures thereof. These biomolecules and their derivatives are used in drug discovery and chemical biology, to develop…

Anthe Janssen graduated ‘summa cum laude’ for the master’s programme Chemistry.He used NMR methods to gain insight in the syntheses and behavior of bio sugars. With this knowledge future therapeutics and research tools in hemical and medicinal biology can be developed. Anthe was awarded € 2.500.

PURPOSE: In the present study we investigated the root-cause of an interference signal (100-200 nm) of sugar-containing solutions in dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) and its consequences for the analysis of particles in biopharmaceutical drug products.

During stepwise synthesis of sugar chains, two stereometric variants are formed at each step unless the steps are steered. Through an extensive investigation, Daan Hoogers investigated a new steering mechanism, for which he was nominated for the Young Star Award 2021.

At Leiden Bio Science Park (LBSP) Leiden University works together with the business community, the LUMC and the Municipality of Leiden.

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

The master’s programme of Bio-Pharmaceutical Sciences at Leiden University examines the research area of bio-pharmaceutical sciences and drug research. It offers seven specialisations ranging from BioTherapeutics to Industrial Pharmacy.

As a student of Bio-Pharmaceutical Sciences, you have a strong interest in drug development: from the onset of diseases to the effects of individual drugs in the body. Is that true for you? Then, Bio-Pharmaceutical Sciences might be the right study programme for you!

We investigate reaction systems, a novel computational model gleaned from the biochemical reactions taking place in living cells and information processing in nature.

This page provides information to support your application for the Master's programme of Bio-Pharmaceutical Sciences.

PhD candidates carry out a programme of independent research and additional limited) course work, culminating in production of a PhD thesis in typically 4 years.

Conservation of biodiversity is one of the main challenges today. A higher degree of biodiversity results in ecosystems that can withstand adverse conditions and better provide essential ecosystem services. This is the case for both agricultural and natural systems.

Leiden Bio Science Park (LBSP) is the largest knowledge centre in the Netherlands in the field of life sciences & health and is also highly regarded internationally. The clustering of high-quality education, research, care and business attract students, scientists and entrepreneurs from all over the…

The master’s specialisation Bio-Pharmaceutical Sciences and Education at Leiden University combines fundamental chemistry research with an excellent education in becoming a Chemistry teacher.

We are interested in understanding the mechanics of soft materials, of which biological materials are prominent examples.

The master’s specialisation Bio-Pharmaceutical Sciences and Business Studies at Leiden University combines fundamental and applied research with different aspects of business studies.

The master’s specialisation Bio-Pharmaceutical Sciences and Science Communication & Society at Leiden University is a two-year programme which combines research training in chemistry with one in techniques of communication.

The current hepatitis B vaccines need to be stored and transported under refrigerated conditions (2-8 degrees C). This dependence on a cold-chain is highly challenging in areas where hepatitis B virus infections are endemic.

Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…

Playing a musical instrument is generally considered to be a complex human behaviour involving the integration and coordination of a broad range of human functions such as perception, imagination, memory, information processing, emotion, communication, and dexterity.

The Leiden Bio Science Park (BSP) will become a real campus in the coming years, with more houses, and attractive places where scientists, students and entrepreneurs can meet to discuss their plans.

When following a course on archaeology of the Crusaders, five archaeology students were presented the unique opportunity to create a small exhibition at the National Museum of Antiquities. The coronavirus situation made a complex task even more challenging. ‘We had to work through the lockdown with…

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.

The high prevalence of pure red cell aplasia in Thailand has been associated with the sharp increase in number of recombinant human erythropoietin (rhEPO) copy products, based on a classical generic regulatory pathway, which have entered the market.

In the latest newsletter of the Leiden Bio Science Park you can find information about participating in a new European Research Project, the 25th Lab Career Event and the 'Kennisfestival 2009'!

Ida Haisma has been appointed Director of the Leiden Bio Science Park. She will lead the transformation of the Leiden Bio Science Park from science park to innovation district. To this end, she will set up a new park organisation and act as the spokesperson for the park.

The Leiden Bio Science Park is nominated for Best Business Park in the Netherlands. The competition is set up by 'Bedrijventerrein Magazine'.

Although sugars are widely used in biological and medical research, their synthesis is still badly understood. Jeroen Codée has received a Vici grant of 1.5 million euros for systematically studying the production of sugars. ‘I want to genuinely understand the reactions.’

Many students cycle past the companies of the Bio Science Park every day, but what actually happens behind those doors? And is there a future there for students after their graduation? The Bio Science Park Excursion answers these questions.

American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.

Professor Fons Verbeek of the computer science and biology institutes at Leiden University has the fascination to visualize everything we can not see immediately. At SleutelstadFM he tells us that by converting 2 dimensional (2D) images to 3 dimensional (3D) structures, research is carried out into…

For Harry Flore, chair of the LBSP business asociation and CEO at Hal Allergy, the Leiden Bio Science Park (LBSP) has no secrets. But he can well imagine the park is a black box for some staff and students at the university: 'I welcome collaboration on all fronts.'

At the start of the COVID-19 pandemic, researchers from 15 departments at Leiden University Medical Center (LUMC) realised they could do more for patients if they joined forces. This is how the BEAT-COVID group has been able to rapidly gain knowledge about COVID-19, the role of the immune system and…

Pharma company Janssen has begun construction on a new office and lab building at the Leiden Bio Science Park. The first pile of the 13,500 square metre building has been driven into the ground.

International pharmaceuticals company Grünenthal is to open an innovation hub on the Leiden Bio Science Park. The hub will make it easier for scientists and drug developers to work together.

On 8 October, the Leiden Bio Science Park won the Menzis award for the Best Business Park 2009. The jury particularly praised the fact that 25 years ago when the park was founded, the choice was made in favour of the biomedical life sciences, a specialisation still successful today.

On 23 November, more than 70 students visited companies at the Leiden Bio Science. This second edition of the BSP Excursion included a fundamentals track and had a special focus on start-ups.

Hermen Overkleeft and his colleagues Gideon Davies (University of York) and Carme Rovira (University of Barcelona) will receive a 9.1 million euros Synergy Grant from the European Research Council. Together, they will form the Carbocentre Synergy team for research into enzymes that work on glycans:…

A large new campus square on the Leiden Bio Science Park will be used for a range of activities for students, staff and Leiden residents, a knowledge festival, shows and sporting activities, for instance.

The university campus at Leiden Bio Science Park will change rapidly over the next few years. A short film shows the transformation to a full campus. See what this mix of new university buildings, student accommodation and restaurants and cafés will look like. And sustainability and biodiversity won’t…

The MORE project covers the development of the new entrance area for the Leiden Bio Science Park. Partners Leiden University, the Municipality of Leiden and the Amstelveen-based development agency Yisheng signed the agreement on 18 March, marking the official start of the project.

New housing in old labs and striking architecture for University buildings and high-tech companies, not to mention waterside parks. An exhibition in Oude UB shows the radical changes that are in store for the Leiden Bio Science Park over the coming years.

The Leiden Bio Science Park (LBSP) is very important not only for the city of Leiden but also for the Leiden region and the Netherlands as a whole. This is the finding of an investigation conducted by the Leiden-Leiderdorp Audit Committee. The large-scale development of the LBSP in recent years has…

It is a warm day. The sun is shining brightly while biologist Marco Roos makes his way through the bushes towards a peculiar little plant. Insects buzz, birds chirp. In the background rises the LUMC: at the Bio Science Park in Leiden, people and nature come together in a special way.

Promotor: W. Jiskoot, Co-promotor: A. Hawe

We aim to develop A. niger strains that produce more starch degrading enzymes even in the absence of starch.

25 Years ago, the Center for Bio-Pharmaceutical Sciences was founded at Leiden University; one year later, in 1985, the education program of Bio-Pharmaceutical Sciences started. On Friday September 18th, this was celebrated with a Symposium, an anniversary booklet, and a grand party.

Is it possible for sugar patterns on cells to activate the immune system to combat cancer?