In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

Politics and Aesthetics is one of the six research themes of the LUCAS Modern and Contemporary cluster.

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Social evaluative fears during adolescence

Founded in 2001, Zumba Fitness is a global lifestyle brand that fuses fitness, entertainment and culture into an exhilarating dance-fitness sensation! Zumba® exercise classes are " fitness-parties " that blend upbeat world rhythms with easy-to-follow choreography, for a total-body workout that feels…

Bringing together scholars from Russia, the United States and Europe, this collection of essays is the first to explore the slippery phenomenon of post-Soviet nostalgia by studying it as a discursive practice serving a wide variety of ideological agendas.

Dividing Worlds: Tsunamis, Seawalls, and Ontological Politics in Northeast Japan

The department of World Archaeology combines research and education about regions all over the world, from Human Origins to the Middle Ages, and from Europe, to Asia, Africa and the America’s. That broad range in time and space makes the department a dynamic pluriform community with many different approaches,…

This book aims to understand cultural transitions and negotiations between art and politics from 1989 to 2020 through analysis of a series of Cuban novels.

We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.

Promotor: Prof.dr. G.P. van Wezel

What are the risks of nanoparticles?

In the Master's programme Crisis and Security Management, specialisation Governance of radicalism, extremism and terrorism we focus on the academic body of knowledge on different form of protests, contention, resistance and violence. We explore and explain the emergence of radical and extremist move…

PhD at the Natural Product Laboratory, Institute of Biology, Leiden University - the Netherlands

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

Extending our current arsenal of antibiotics is key to staying ahead in the arms race between humans and resistant bacteria.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

The programme consists of 60 EC, to be completed in one year.

Plant Sciences' contribution to the Evolution & Biodiversity research theme is to understand what are the key drivers of plant biodiversity during evolution with a focus on plant life history and resilience traits and develop tools to restore and maintain plant biodiversity.

The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…

How did slaves in the eighteenth century manage to empower themselves and their kin, and why did this become all the more difficult in the nineteenth century?

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?

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What socio-cultural transformations did indigenous communities in the Lesser Antilles undergo from the late precolonial to the early colonial period in response to Amerindian­ European-African cultural encounters? How did Amerindian populations realign themselves in response to the colonisation…

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Increasing resistance and a lack of new antibiotics are a serious problem for public health. Against this background, Gilles van Wezel of the Institute of Biology Leiden is looking for new medicines. Together with former PhD student Changsheng Wu and colleagues he discovered the special antibiotic lugdunomycin,…

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

This thesis describes a study from both a theoreticaL and an experimental point of view.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Mr. Ade Jaya Suryani defended his thesis on 28 January 2021

This month Ali Shobeiri's monograph, Place: Towards a Geophilosophy of Photography came out at Leiden University Press.

Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?

Jifeng Liu defended his thesis on 2 February 2017

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.