Leiden University stands for high quality research. Integrity and reliability in the way we conduct research are core beliefs in Leiden.

The subject areas covered encompass functional genomics, signal transduction, cellular differentiation, development, host-microbe interactions and animal behaviour.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

The aim of this research area is to be able to predict human drug response on the basis of mathematical models that are developed using preclinical experiments and prior knowledge.

Lezing, Studium Generale

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Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

In Dutch TV programme Early Birds, Marvin and Kevin Groen (26) showed viewers areas of nature in the city that often go unnoticed. These good-natured brothers - twins, in fact - were a big hit with the viewers. How much influence do they have on one another's studies and work?

Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…

How can we organise society so as to keep our planet habitable for us and for all other life forms around us? To answer this question, Leiden researchers collaborate across disciplines, from biology to data science, and from environmental economy to archaeology.

Coral reefs throughout the world are under threat. After studying the reefs in Malaysia, Zarinah Waheed concluded that there is room for improvement in coral reef conservation. PhD defence 22 November.

The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'

Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.

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Archaeological research of coastal farming communities on the southern North Sea coast, 2000-800 BC

This research network aims to promote cross-regional collaboration in the field of cultural history in early modern Asia at the intersections of visual, material, textual and aural culture.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

Do understudied animals contain hidden species?

We recognize the importance of communicating about our scientic work to the general public and we enjoy doing so. Recently, we received funding from the Pilot fund Science communication by scientists: Appreciated! (with members of Change Leiden) to engage children and adolescents in science communication…

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Do humans and zebra finches share cognitive mechanisms that are important for speech perception?

Observational, cognitive and physiological measurements in social contexts.

We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.

The handbook is a wide-ranging survey of a crucial period in prehistory during which many social, economic, and technological changes took place. Written by specialists in the field, the book provides coverage both of the themes that characterise the period, and of the specific developments that took…

From Complex Hunter-Gatherers to Early Urban Societies

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

Promotor: E.F. Smets Co-promotor: J. Geml

Ecotox is located in an ambitious surrounding at the Leiden University. It is an initiative of both institutes Institute of Environmental Sciences (CML) and Institute of Biology Leiden (IBL).

Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?

Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.

Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?

Karmaşık Avcı-Toplayıcılardan Erken Kentsel Toplumlara

This subproject of 'From Homo Economicus to Political Animal' analyzes Greek economic thinking of the Hellenistic period.

Consequences for sediment stability and seston trapping

Patterns of paleomobility in the Caribbean were studied through an inter-disciplinary approach using a combination of archaeological, osteological, mortuary, and isotopic data.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Provides a cutting-edge comparative political economy analysis of welfare and inequality across ten East Asian countries.

Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?

Pursuing Whiteness in the Colonies offers a new comprehension of colonial history from below by taking remnants of individual agencies from a whiteness studies perspective. It highlights the experiences and perceptions of colonisers and how they portrayed and re-interpreted their identities in Afric…

What did it mean to be enslaved in in the Indian Ocean world in the 18th and 19th centuries? Over the last decades, historians have mined French, British, Portuguese and Dutch records for quantitative data on the European slave trade. This project focuses on the experience of being a slave and seeks…

The overall aim of CAM-PaC is to contribute to solving the socioeconomic and health challenges of PDAC by an integrative and systematic functional analysis of pancreatic cancer candidate genes. CAM-PaC will develop novel cellular and animal models, as well as novel strategies to analyse and integrate…