1,053 zoekresultaten voor “affinity selection mass spectrometry” in de Publieke website
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Teaching
Disseminating to the future generation of researchers the multidisciplinary working practices, expertise and scientific view that has been developed in research within the Plant BioDynamics Lab over the past years is an important objective in our collaborative efforts. The research papers of PBDL bring…
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Design, synthesis and application of paramagnetic probes for protein structure studies
The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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Strategy
The division of Drug Discovery and Safety combines the former divisions Toxicology and Medicinal Chemistry.
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Islam at 250: Studies in Memory of G.H.A. Juynboll
Islam at 250: Studies in Memory of G.H.A. Juynboll is a collection of original articles on the state of Islamic sciences and Arabic culture in the early phases of their crystallization.
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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In silico characterization of a GPCR focused library
Supervisor: Gerard van Westen
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Child Law (LL.M.)
The master’s programme 'Jeugdrecht' considers topics like child abuse, child refugees, bullying via social media, adoption and divorce and aims to make a difference in the lives of the youngest members of our society.
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Causing a stir: Radiative and mechanical feedback in starburst galaxies
Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf
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Formulation of biopharmaceuticals
Formulation of biopharmaceuticals
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The Connection Between Mass and Light in Galaxy Clusters
Promotie
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Admission requirements
To be eligible for African Studies (research) at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Classics (research) at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Arts, Literature and Media (research) at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Hebrew and Aramaic Studies (research) at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Assyriology (research) at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Asian Studies (research) at Leiden University, you must meet the following admission requirements.
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Binding kinetics
A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…
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Admission requirements
To be eligible for Middle Eastern Studies (research) at Leiden University, you must meet the following admission requirements.
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Hit Discovery
The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.
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Admission requirements
To be eligible for Media Technology at Leiden University, you must meet the following admission requirements.
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Admission requirements
To be eligible for Egyptology (research) at Leiden University, you must meet the following admission requirements.
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Master students Industrial Ecology selected for EU-project for sustainable start-ups
Four students of the MSc Industrial Ecology have recently been selected to participate in the accelerator programme of the EIT Climate-KIC, which helps sustainable start-ups. The four students use coconut husks to develop sustainable boards, which can be used to make furniture.
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Old protein distinguishes bone fragments of Neanderthals
Bone remains that are thousands of years old are often too fragmented to be identified. PhD candidate Frido Welker is the first person to be able to distinguish human bones from one another on the basis of old proteins. PhD defence 18 May.
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10 start-ups from The Hague selected for Venture Academy
Centre for Innovation launched the Venture Academy on 22 February 2017. The Venture Academy helps students of The Hague to create their own job. The aim of the Venture Academy is to bridge the gap between student entrepreneurship and small and medium sized enterprises. It offers a 5 month programme…
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Giovanni Gruni selected to act as discussant at the Society of International Economic Law PEPA Conference in Tilburg
Dr. Gruni was invited by the Society of International Economic Law (SIEL) to join their PEPA conference which will be held in Tilburg on the 20th and 21st of April.
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Adaptive responses to environmental changes in Lake Victoria cichlids
Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte
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Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
Promotie
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The promise of organization. Political associations, 1820-1890, debate and practice
The central theme of the NWO-project ‘The Promise of Organization’ is the evolution of political organization during the 19th century. We focus on the enthusiasm, arguments and concrete activities of the organizers as well as the criticism offered by opponents of modern political organization.
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Award for finding the most extreme stellar object in the Universe
Joseph Callingham from the Leiden Observatory receives the Louise Webster Prize for outstanding post-doctoral research. The prize is awarded by the Astronomical Society of Australia for Callingham’s search for the most extreme object in the Universe.
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COVID-19 and Its Effect on Mass Tourism in World Heritage Cities
Lezing, Re-Scape Colloquium
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Vibration Isolation
To be able to measure small forces or small deviations from Boltzmann, the external vibrations at the resonance frequency must be very low. To achieve this, we have developed a very soft vibration isolation system and combine it with several other measures to reduce vibrations in our dilution refrigerators.…
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European and International Media Law
This book is the first to incorporate current academic literature and case law on European, transnational, and international media law into a comprehensive overview intended primarily for students.
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Popular Music in Southeast Asia
From the 1920s on, popular music in Southeast Asia was a mass-audience phenomenon that drew new connections between indigenous musical styles and contemporary genres from elsewhere to create new, hybrid forms. This book presents a cultural history of modern Southeast Asia from the vantage point of popular…
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Spectroscopy of two-field inflation
This thesis is about cosmological inflation and its relation to observations.
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Career
The field of science communication is very broad. Below is a list of organisations where SCS students can fulfill internships or where alumni have found jobs.
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On Products of Linear Error Correcting Codes
In this thesis we study products of linear error correcting codes.
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About
The Global Abolitionisms Network is an international network of scholars working on antislavery activism and abolitionism. It is affiliated to the recently established Leiden Slavery Studies Association.
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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Self-Portrait with Gorget
In this penetrating self-portrait dating from around 1629, Rembrandt presents himself as an aristocratic young man. He enrolled in Leiden University as a student of the arts in 1620, but whether he actually attended lectures is unknown. In his paintings and prints, he incorporated many topics that are…
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Camille Lefebvre selected as one of the 30 finalists vying for a spot in scholarship of The Pierre Elliott Trudeau Foundation
Camille Lefebvre has been selected as one of the 30 finalists vying for a spot in the 2022–2025 scholarship of The Pierre Elliott Trudeau Foundation.
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Admission requirements
The master’s degree programme Developmental Psychopathology in Education and Child Studies (research) is an academic, not a vocational programme. It offers research based knowledge about education and child development.
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Gauss's theorem on sums of 3 squares, sheaves, and Gauss composition
Promotor: Bas Edixhoven, Promotor: Qing Liu
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The Movement of Showing
Indirect Method, Critique, and Responsibility in Derrida, Hegel, and Heidegger. Explores why Derrida, Hegel, and Heidegger conceive of their thought as a “movement” rather than as a presentation of results or conclusions.
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Drug Discovery & Safety
In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.
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Structural characterization of bacterial proteins involved in antibiotic resistance and peptidoglycan biosynthesis
This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Cannabinoid receptor 2 as a ‘drugable’ target: kinetic profile of novel receptor ligands
Supervisor: Andrea Martella