127 zoekresultaten voor “abnormal hieratic” in de Publieke website
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The development and prevention of social anxiety in youth
What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?
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Admission requirements February 2023
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements February 2023
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements February 2023
To be eligible for Child and Adolescent Psychology at Leiden University, you must meet the following admission requirements.
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Kinetic profiling of positive allosteric modulators of the mGlu2 receptor
Supervisor: Maarten Doornbos
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The development of public speaking anxiety in youth
Does the public speaking anxiety that many youngsters experience originates from specific characteristics in their earlier development?
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Profiling Endophenotypes in Social Anxiety Disorder – a family study
The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…
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Former Leiden Colleague Sven Vleeming honored with ‘Festschrift’
On February 2nd, 2018, Professor Sven P. Vleeming of Trier University was presented with a ‘Festschrift’ to celebrate his retirement last summer. The book was presented to him, in the presence of friends and colleagues from the Netherlands and abroad, by the editors: his former Leiden colleagues Koen…
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Text in Context
Recontextualising the Papyri from Roman Soknopaiou Nesos / Dimê (Fayyum, Egypt)
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Earliest known alphabetic word list discovered
A flake of limestone (ostracon) inscribed with an ancient Egyptian word list of the fifteenth century BC turns out to be the world’s oldest known abecedary. The words have been arranged according to their initial sounds, and the order followed here is one that is still known today. This discovery has…
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Major international study links genes to brain structural changes over time
There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.
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Online exhibition
TEXTS FROM ANCIENT EGYPT. Highlights from the Collection of the Leiden Papyrological Institute. Online exhibition on the occasion of the 80th anniversary of the foundation ‘Het Leids Papyrologisch Instituut’ in 2015.
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Galactofuranose biosynthesis in the filamentous fungus Aspergillus niger
This project aims to further understand the molecular details related to the biosynthesis and function of Galf containing glycoconjugates in fungal Aspergillus spp.
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Social Anxiety and Normal Development
Why does social anxiety increase in adolescence and how does it grow out of control in some adolescents?
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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NWO Projectruimte for physicists Schalm and Zaanen
NWO has awarded a €392k Projectruimte grant to physicists Koenraad Schalm and Jan Zaanen to study ‘strange metals’. These materials are alleged to follow the bizarre laws of quantum mechanics even at everyday length scales.
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Veni Grant for Lucia Bossoni
Postdoc Lucia Bossoni has received an NWO Veni grant to research brain diseases for the next three years. She will work in labs at both the LUMC and the Leiden physics institute.
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Extreme obesity demands tailor-made medication
Doctors and pharmacists should take greater account of obesity when dosing medicines. The distribution in the body and the breakdown of a medicine can vary considerably in obese patients. This is stated by clinical pharmacologist Catherijne Knibbe in the Annual Review of Pharmacology and Toxicology.
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Specialised immune cells have potential for new cancer immunotherapies
Researchers from Leiden University Medical Center (LUMC) and Netherlands Cancer Institute (NKI) have discovered how specialised immune cells can detect and remove cancers that are ‘invisible’ to the conventional defence mechanisms of the immune system. Their work has been published in Nature. The findings…
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Admission requirements September 2023
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements September 2023
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements September 2023
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements September 2023
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Admission requirements September 2023
Is this the master's specialisation of your choice? Please read here about the admissibility for this programme.
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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Role of Chemokine Gradient Sensing in Ewing Sarcoma Progression, Angiogenesis and Immune Targeting
What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?
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New Methods for (f)MRI Analysis
Analysis of neuroimaging data requires multiple steps where statistics play a crucial role. The MRI methods research group develops new statistical methods that are accurate, transparent and easy to use.
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Animal welfare
We carry – and also feel – great responsibility for our laboratory animals. Animal welfare is very important to us. You can read below how we safeguard the welfare of our laboratory animals.
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Publications
Electronic versions of our publications can be obtained by sending an e-mail to Esther van den Bos: bosejvanden@fsw.leidenuniv.nl
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‘We haven't finished with Tutankhamun's tomb yet'
Sensational, is how Leiden Egyptologist Olaf Kaper described the discovery of two new chambers in the tomb of pharaoh Tutankhamun. He hopes that a second set of scans will confirm their presence unequivocally.
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Fundamental and translational medical biochemistry
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Logos in ancient Egypt
The ancient Egyptians knew about marks as well as script. The New Empire (ca. 1550-1070 BC) in particular provides a rich harvest. The script has now been deciphered, but the same does not apply to the system of marks used at the time. Egyptologist Ben Haring has been awarded a subsidy by NWO from the…
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New book reflects on power and normality
Who determines what is wrong with children and how they develop? Educator and sociologist Annemieke van Drenth wrote a book about this that will be released on 10 June. In it, she uses the history of the school for ‘idiotic children’ in The Hague to investigate how special children were identified in…
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‘Genetic variants could help determine whether breast cancer is hereditary’
We already know a lot about genetics and the risk of breast cancer. But much still needs to be done in breast cancer genetics to improve the prognosis and make sure women at high risk aren’t missed. This is what Professor by Special Appointment Marjanka Schmidt will say in her inaugural lecture on 4…
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Andrew Webb receives 2017 Simon Stevin Master Prize
Andrew Webb, Professor of MRI Physics at LUMC and teacher at the Physics education at Leiden University, has been awarded the 2017 NWO Simon Stevin Master Prize. The prize includes a cash award of 500,000 euros. Webb is planning to use the prize to develop new MRI techniques that allow diseases to be…
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CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mi
Publication by: Amanda Foks, Gijs van Puijvelde, Jolien Wolbert, Mara Kröner, Vanessa Frodermann, Thomas van der Heijden, Peter van Santbrink, Louis Boon, Ilze Bot and Johan Kuiper. Cardiovascular Research. 2016;111(3):252-261.
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New insights into characteristics of Conduct Disorder with "limited prosocial emotions"
In a recent study, Dr. Moji Aghajani and colleagues show that adolescents with a severe form of Conduct Disorder (CD) -with limited prosocial emotions- require an unusually large amount of brain capacity to read emotional faces. These effects were found in comparison to CD youth without limited prosocial…
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Four Leiden University researchers receive Rubicon Grants
Four Leiden researchers, who have recently obtained their PhDs, will receive a Rubicon Grant from NWO to conduct research abroad. A total of 22 scientists have received Rubicon Grants. This grant aims to provide young, promising scientists with international research experience.
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Distress and insolvency
Creation of a good business environment, promotion of trade and investment are among the top priorities for many governments. Due to risks intrinsically connected to entrepreneurial activities, companies may experience financial difficulties and become insolvent. When it happens, the question of whom…
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Tracing cancer with a simple blood test
Thanks in part to the persistence of a Leiden research group, cancer could be detected in the near future with just a single drop of blood. Not only can the diagnosis be determined at an earlier stage, but the blood test is also cheap, fast and patient friendly. The first results of this method seem…
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Introducing: Monika Baar
Monika Baar started working in Leiden in September 2015. She's currently the project leader of the ERC Research Project 'Rethinking Disability'.
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Brain changes underlying social anxiety: numbers count!
In a recent mega-analysis, researchers from Leiden University aimed to clarify the contradictory findings of research into social anxiety disorder. They found that to obtain reliable research results having the largest possible sample size is important. Publication in NeuroImage:Clinical.
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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Ten thousand types of plant outgrowths bundled
For nine years he worked on the three-volume standard work Plant Galls of Europe. It yielded 2300 pages about 10,000 species of European galls, abnormal outgrowths in plants caused by parasites. Hans Roskam from the Institute of Biology Leiden: ‘The abundance of galls says something about the natural…
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Keyring in your hand when walking down the street alone? 'Many women are always on guard'
A cover over your drink in the pub, deodorant as pepper spray or headphones to avoid hearing catcalling: many women use everyday objects to feel safer in public spaces. Student Anne van der Linden made an online exhibition about this.
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The Human Side of Homicide
On 28 February, Marieke Liem, Associate Professor at the Institute of Security and Global Affairs, appeared as a guest on the Dutch NPO Radio 1 Brainwash Podcast to discuss the 'big homicide questions' she is trying to find the answers to.