By detecting the tiny forces between a micrometer sized magnet and the spins of hydrogen nuclei, we can do MRI with a volume resolution that is approximately 12 orders of magnitude better than a conventional MRI.  

Dave R. Stikkolorum, Michel R.V. Chaudron, Oswald de Bruin won the Best Paper Award of the Model Gamification Contest at the ACM/IEEE Models 2012 Conference for their paper: The Art Of Software Design, a Video Game for Learning Design Principles.

Promotie

Cosmologists have many possible models for the Universe, of which only one can be true. A new flowchart will eliminate some of them when two specific Universe features are accurately measured. Publication in Physical Review D on 7 November.

In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.

The Faculty of Archaeology experiments with innovating their teaching methods, using 3D scans and visualisation technology to enable active learning. 'It makes archaeological material more accessible. Especially when it comes to fragile materials, it allows nearly anybody to analyse them.'

The financial system needs complexity theory to predict economic crises like the 2008 meltdown. An international team of scientists, including Leiden physicist Diego Garlaschelli, state this in a paper published in Science on February 19th.

Professor Carlo Beenakker has been awarded a FOM Projectruimte subsidy to build a theoretical model of a majorana gun, a very promising instrument for quantum computers.

Since 2013, the National Natural History Museum of the Netherlands, Naturalis Biodiversity Center, is unearthing the largest bonebed of the horned dinosaur Triceratops discovered so far. In order to answer questions about sedimentology, taphonomy and palaeobiology, palaeontologists and geologists collaborated…

Should the background of the painting remain blue or be restored to its original gold colour? PhD candidate Liselore Tissen will be using 3D prints and eye-tracking software to answer this question. NICAS is giving her a grant of 18,000 euros to accomplish this.

What if you could watch a CT scan live, instead of analysing the images afterwards? If it is up to the Leiden mathematician Jan-Willem Buurlage, that will soon be a reality. He is developing methods to make the algorithms behind 3D scans faster. Quite a challenge: ‘Just like mathematicians, computers…

The main methodological aspects of the use of stepwise LCA estimators under different circumstances.

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Cardiovascular disease is the leading cause of death worldwide.

As a lecturer of a block 4 course, osteoarchaeologist Dr Rachel Schats is preparing to give her education remotely. For this she uses Kaltura, Leiden University’s video platform. While she is new to remote teaching, like most of the University’s lecturers, she already has some tips and tricks based…

Lezing, Digital Archaeology Group

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

Promotor: Prof.dr. R.M.H. Merks

Experts from several disciplines have raised concerns about the use of seemingly precise models to guide policies in matters as complex as the current Covid-19 pandemic. 22 scholars wrote down five principles on how to responsibly use scientific models. This comment was published in Nature on 24 June…

Promotor: A.P.IJzerman Co-promotor: A. Bender

A full overview of all loans and debts between banks would help preventing a new financial collapse. But banks do not provide this information. An econophysics model by Diego Garlaschelli and collaborators reconstructs the most probable situation and finishes first place in two independent tests.

Pharmacogenetics is nowadays increasingly incorporated in the clinic to better predict pharmacokinetics and optimize dosing regimens of drug treatments. While this approach has been successful and improved our prediction of drug metabolism, drug levels within patients may still commonly deviate between…

The precolonial inhabitants of the Caribbean islands communicated, travelled, and exchanged objects and ideas along an expansive inter-island network. New methods of computer modeling shed light on these networks. Emma Slayton is set to discuss her work on this topic at her Defense on the 12th of Se…

Practical applications for the reconstruction of the past

Warisa started as a Postdoc researcher at the Department of Environmental Biology of CML in March 2020.

Linking Empirical Academic thinking with Legal Practice. Internationally and particularly in the Netherlands. By René Orij, April, 2016.

Archaeologists often use the percentages of heat-affected stone or bone artifacts found at archaeological sites as a way to determine how frequently fire was used by the inhabitants. Andrew Sorensen and Fulco Scherjon have come up with a computer model called 'fiReproxies' to simulate how fires used…

A new study in Nature Plants has explored the most important organising principles that control vegetation behaviour. The insights from this study can be used to improve predictions on climate change. Leiden scientists Peter van Bodegom and Nadia Soudzilovskaia participated in the study.

In July, 2018, the Institute of Biology Leiden hosted the 11th conference of the Zebrafish Disease Models Society (ZDMS), an international association dedicated to the advancement of basic and clinical research using zebrafish disease models. More than 350 researchers from all over the world gathered…

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.

Many organisations have a biased workforce, even though diversity has so many advantages. Australian and Dutch researchers, including Leiden psychologist Romy van der Lee, have developed a solution based on a mathematical model. They published their findings in PLoS One on 28 July.

This research group is interested in the physics of living cells, especially their cytoskeleton dynamics under defined external stimuli.

The aim of ANCIENT CHARM was to develop neutron-imaging techniques and the associated equipment, and help establish neutron imaging as a mainstream archaeological analytical technique. In particular, one of the goals was a new imaging technique which called neutron resonant capture imaging combined…

The Honours Academy has recently started working with the new visual technology Virtual Reality (VR). 'It is important to look beyond your own borders and to keep on experimenting. It may not work out, but at least you tried.'

Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?

The two-years master’s specialisation System Biomedicine and Pharmacology at Leiden university focuses on predicting drug response with computational modelling, developing individualised therapies, and developing innovative analytical tools for personalised health strategies.

An overview of research themes and projects at ABS.

The ambition of the Analytical BioSciences and Metabolomics group led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies…