964 zoekresultaten voor “yeast screening” in de Publieke website
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Microfluidic 3D cell culture for high throughput screening
Promotie
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Screening the Stans: Film and Fiction in Central Asia
Kunst en Cultuur
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Development of organ-on-a-chip systems for translational and personalized medicine
We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.
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Discovery of metastasis promoting candidate drug targets
Discovery of metastasis promoting candidate drug targets
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Human skin equivalent barrier optimization
The currently available in vitro generated human skin equivalents resemble the human skin in many aspects. However, some essential barrier characteristics do not fully mimic the native barrier. Consequently, the human skin equivalents cannot be used for screening of drugs for skin penetration.
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Crystal Cave
X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.
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Imaging
The imaging group focuses on bio-imaging, image analysis and visualization.
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Collaborations
The Molecular Physiology group collaborates with both international public-private and academic institutions.
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Film screening followed by Q&A with filmmakers
Lezing
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Activities
The CEES Centre regularly hosts (guest) lectures, roundtables, and film screenings.
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ZF-CANCER - Developing high-throughput bioassays for human cancers in zebrafish
How can zebrafish research help to understand and fight human cancer?
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Opening PoreLab
PoreLab is officially opened on November 1st, 2016. This new lab located at the Sylvius Laboratory will be working with the latest DNA analysis technology and will bring science, education and industry together to explore practical applications with the MinION.
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Biophysicists unravel exact folding of a single gene
The way genes are folded determines their activity in our body. Leiden biophysicists are now the first to unravel this structure molecule-by-molecule. Publication on December 1st in Nature’s Scientific Reports.
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Contact
Interested in working with the Dutch Extract Library?
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Yellow Lab
A 24 person classroom on the floor 0 of the Pieter de la Court building. Designed for groupwork, rolling, flexible tables and chairs are arranged around shared monitors. Each group has a small whiteboard. The frontal projection point has a short-throw projector with motion tracking and live annotation.…
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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Development of thermostable lyophilized inactivated polio vaccine
The aim of current study was to develop a dried inactivated polio vaccine (IPV) formulation with minimal loss during the drying process and improved stability when compared with the conventional liquid IPV.
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Identification of novel targets in prostate cancer progression
Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen
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Chemokine signaling mechanisms underlying inflammation and infection control: insights from the zebrafish model
This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.
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Dancing with the Stars
This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.
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Kinetics for Drug Discovery: a Case for the Adenosine A3 receptor
Supervisor: Lizi Xia
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Receptor Residence Time
Research question
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
- Summitry
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Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
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Kinetic profiling of positive allosteric modulators of the mGlu2 receptor
Supervisor: Maarten Doornbos
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Documentary screening on a mining conflict in KwaZulu-Natal: This land
Kunst en Cultuur, Film screening
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Screening documentary ‘Breaking News: Spending the Same Day in Two Different Newsrooms’
Lezing
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Second layer of information in DNA confirmed
Leiden theoretical physicists have proven that not only the genetic information in DNA determines who we are, but also DNA’s mechanics. Helmut Schiessel and his group simulated many DNA sequences and found a correlation between mechanical cues and the way DNA is folded. Publication in PLoS One.
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Promotie
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A screening based approach to find new paths for targeted treatment in chondrosarcoma
Promotie
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
Promotie
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and Neonatal Alloimmune Thrombocytopenia: towards implementation of screening in pregnancy
Promotie
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search of Biomarkers for Leprosy Diagnosis: In silico identification, screening & field application
Promotie
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Screening the War on Terror: The Politics and Aesthetics of Torture in American and European Cinema
Promotie
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Word as Image: Waka Inscription on the Folding Screen at the Turn of the 17th Century in Japan
Lezing