On the 10th of November, Sara Petrollino succesfully defended her PhD-thesis and graduated. LUCL congratulates Sara on this great result.

This dissertation presents a description of Sandawe, a Khoisan language spoken by approximately 60 000 speakers in Dodoma Region, Tanzania.

The English language and culture study programme also exists in the form of a part-time programme.

Beauty is a central concept in the Italian cultural imagination throughout its history and in virtually all its manifestations. It particularly permeates the domains that have governed the construction of Italian identity: literature and language.

What can languages spoken in the Lesser Sunda Islands today tell us about the histories of its various population groups?

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

Behrouz Karoubi defended his thesis on 15 June 2016

The general objective of this thesis is to determine a typology of verbal derivation in Ethiopian Afro-asiatic languages.

On October 9th, Peter Alexander Kerkhof succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Peter Alexander on this great result.

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

This research examines the social, political, and cultural forces that structure people’s responses towards accented speech, and further uses the accent as a focal point to theorize the interrelation between language and body.

This dissertation provides a description of the language Tadaksahak as it is spoken by the Idaksahak, a people group of about 30,000 living in the most eastern part of Mali and several isolated places in western Niger.

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

This dissertation provides a formal description of the relationship between diatopic/diachronic micro-variation and phonologization through analysis of the phonetic/phonological properties of unstressed vowel reduction and vowel insertion in two Northern Italian dialects.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Promotores: Prof.dr. G.R. de Snoo & Dr. R. Heijungs

Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model

Geesteswetenschappen, Centre for the Arts in Society

The AAM-LR project aims at building a demonstrator of a web service that will help filed researchers to annotate audio- and video-recordings.

On the 30th of June, Richard L. Boutwell successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Richard on this achievement!

This book offers a linguistic anthropological analysis of multilingualism among the Matsigenka, Quechua, and Spanish languages on the coffee frontier of Southern Peru, set against the backdrop of economic transformation and deforestation in the world’s last great forest.

Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.

In this research project Nizar Rohana analyzes and reflects on taqsīm recordings by two leading figures of ‘ūd playing who were pillars of modern Arabic music, namely the Egyptians Muḥammad al-Qaṣabjī (1898-1964) and Riyāḍ al-Sunbāṭī (1906-1981).

Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…

This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

This 862-page monograph is a grammar of Thangmi, an endangered Tibeto-Burman language spoken in the districts of Dolakha and Sindhupalcok in central-eastern Nepal.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

How can the transport of molecules in living cells help to target medicines at exactly the right place?

Promotie

Promotores: H. Schiessel, G.T. Barkema

Promotor: Prof.dr. M.K. Richardson

My research addresses the function of the much-debated particle -nā in Biblical Hebrew, often translated with “please”, from the point of view of the most important ancient Bible translations (Greek, Syriac, Latin). It combines textual criticism, translation technique, discourse pragmatics, and the…

We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.

What are the capabilities or limitations of traveling between islands and how does this reflect seasonal variation? Is it possible to show higher levels of connectivity between islands based on generated pathways between several sites on two separate islands?

The research focuses on the understanding of symbolic stratigraphy of the land (through time) from the worldview of the People of the Rain (one of the Indigenous Peoples of southern Mexico), by studying contemporary cultural heritage in communities of the Mixtec Highlands.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…

Assessing the feasibility and legitimacy of the current model of global tax governance and the role of the OECD and EU in international tax law-making.

Promotor: F.S. de Boer Co-promotor: P. T. de Gouw

How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?

Studying languages enables you to unearth a lot of valuable information about humans: it reveals our history and explains cultural differences and it even illustrates the process of learning new information. The University is sharing its knowledge of and passion for languages in various new ways, including…

Chapter 1,contains the numerical verification of the Birch and Swinnerton-Dyer conjecture for hundreds of Jacobians of hyperelliptic curves of genus 2, 3, 4 and 5.

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.