Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

Promotor: Prof.dr. G.J. Kroes

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.

Dissociative chemisorption is an important reaction step in many catalytic reactions.

This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…

Promotor: G. J. Kroes

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

Promotores: P. Stevenhagen, L. van Geemen Co-promotor: R.M. van Luijk

Promotor: T.J. Aartsma, Co-promotor: R.N. Frese

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Promotor: Prof.dr. J.W.M. Frenken

Unfolding potential

Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…

Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk

In this thesis integral points on affine del Pezzo surfaces are studied.

Promotor: Peter Stevenhagen

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk

This thesis contains results on the arithmetic and geometry of del Pezzo surfaces of degree 1.In Chapter 1 we give the necessary background, assuming the reader is familiar with algebraic geometry.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

Promotores: G.W. Canters, T.J. Aartsma

Promotor: Prof.dr. H.V.J. Linnartz

Veel kinderen leren niet op een niveau dat aansluit bij hun potentieel om te leren. Diagnostiek in de leerlingbeleiding zou daarom inzicht moeten geven in hoe een kind begeleid kan worden in het verder ontwikkelen van zijn of haar sterke kanten terwijl het tegelijkertijd handvatten biedt voor het ondersteunen…

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer

Aim: To develop and enable application of a practical, flexible, user-friendly platform to provide the scientific community with a tool to generate land surface products and its associated uncertainties and exploit these for data-intensive science.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Promotor: Prof.dr. S.F. Portegies Zwart

Promotor: W.Th.F. den Hollander

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

Promotor: J.W. van Holten

Developing methodes to understand the evolution of patches in natural ecosystems

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

Hoe beinvloed de structuur van één enkel gen de activiteit van genen die gevoelig zijn voor hormonen?