958 zoekresultaten voor “stress response pathways” in de Publieke website
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In de media en onderzoek
Hieronder vind je een overzicht van hoe onderzoekers van de faculteit Governance and Global Affairs en hun onderzoeken in de media verschijnen, en lees je meer over onderwerpen waar de faculteit zich mee bezighoudt.
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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The role of the interleukin 12 family in atherosclerosis
Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
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Impacts of fire on invertebrate species
What impact does a mid-season wildfire have on grassland invertebrates?
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On the geometry of fracture and frustration
Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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Large scale visual search
Promotor: J.N. Kok, Co-promotor: M.S. Lew
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Understanding the uptake and internal distribution of metallic nanoparticles in Danio rerio larvae
The aim is to discover where differently shaped metal nanoparticles distributes in Danio rerio, linking the distribution with genomic responses and so come up with a Mode of Action.
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot
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Modelling the role of cytotoxic T lymphocytes in tumour regression
Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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When materials become critical: lessons from the 2010 rare earth crisis
Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn
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Onderzoek
Het onderzoek van de sectie Gezondheids-, Medische en Neuropsychologie richt zich op de psychologische aspecten van gezondheid en ziekte, en op het ontwikkelen van innovatieve behandelingen.
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Development of Quantitative Nanostructure Activity Relationship (QNAR) Models Predicting the Toxicity of Metal-based Nanoparticles to Aquatic
Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…
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Shaping innate immune responses: mechanisms that control type I interferon production
Promotie
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On shape and elasticity: bio-sheets, curved crystals, and odd droplets
Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.
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The role of autophagy during carbon starvation in Aspergillus niger
Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.
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Webinars
Op deze pagina vindt u het overzicht van zowel de aankomende als de afgeronde alumniwebinars van de Universiteit Leiden. Bij elk afgerond webinar vindt u de link naar de opname.
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Psychologie
Het Instituut Psychologie verzorgt innovatief en interdisciplinair onderzoek en onderwijs binnen de psychologie en aanverwante vakgebieden.
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Onderzoek
Het Instituut Psychologie verzorgt innovatief en interdisciplinair onderzoek en onderwijs binnen de psychologie en aanverwante vakgebieden. Daarbij ligt de focus op drie grote gebieden: gezondheid en welzijn, ontwikkelen en leren, en sociale, cognitieve en economische besliskunde. Het onderzoek varieert…
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Trauma’s bij pleegkinderen
Gevolgen voor de klas en tips voor de leerkracht
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tract infection: prevention, early detection and attenuation of immune response
Promotie
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CANCELLED: ASCL Seminar: The UN, Women’s Movements, and the Post-Conflict Response to Sexual Violence
Lezing
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Voordrachten
Voordrachten in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus (aug 2017 – aug 2022).
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Cutaneous CD30-positive lymphoproliferations: Therapeutic strategies and prognostic factors
Promotie
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C-SCAPE - Sandy strategies for sustainable coastal climate change adaptation
What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?
- Veelgestelde vragen
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CECILIA2050 - Optimal EU climate policy
Development of scenarios for 2050 detailed in an IO framework
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The Rhetoric of Illusion: Persuasion and Response in Forgery, the Arts and Other Deceptions (1600-1750)
Promotie
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Van stress naar succes: hoe actinobacteriën gebruikmaken van een celwandloos bestaan
Lezing, Online NGL-lezing
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Interactions of nutrients and pesticides and their effects on aquatic macrofauna
Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Green defense against thrips- Exploring natural products for early management of western flower thrips
As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).
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Financial Collateral
In november 2020 is het Engelstalige boek ‘Financial Collateral; Law and Practice’ verschenen. Het boek is gepubliceerd door Oxford University Press en geredigeerd en geschreven door professor Matthias Haentjens. Voorts hebben meegeschreven Anthony Zacaroli (High Court, Chancery Division), Yael Diamant…
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Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Arabidopsis AGC3 kinases and PIN plasma membrane abundance
The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Effect of Nanoparticles on Microbial Catabolism and Community Structure using Biolog techniques
1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?
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Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration
Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.
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Instituut Bestuurskunde
Het Instituut Bestuurskunde van de Universiteit Leiden is één van de grootste en oudste instituten voor academisch onderzoek en onderwijs op het gebied van Bestuurskunde in Nederland en is gevestigd in Den Haag. Het instituut combineert een wereldwijd goede academische reputatie met een centrale positie…
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Beyond random and forbidden interactions : how optimizing energy gain results in morphological matching among subalpine Asteraceae and their
Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.
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Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
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Strategies for Mechanical Metamaterial Design
On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.