1,001 zoekresultaten voor “stress response pathways” in de Publieke website
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The evolution and plasticity of life histories upon variation in nutrition: on aging focused integrative approach
Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)
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Modulation of plant chemistry by rhizosphere bacteria
Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Stress, Obesity and Mood Disorders
Promotie
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Stressed-out Stress Systems
Promotie
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Stout of onhandig? Negatieve attributies van ouders in relatie tot het risico op kindermishandeling
De wijze waarop ouders het gedrag van hun kind interpreteren en evalueren, hangt samen met het risico op kindermishandeling. Deze ouderlijke cognities, ook wel negatieve attributies genoemd, zijn een schakel tussen stress en het risico op kindermishandeling. Marieke Beckerman draagt met haar promotieonderzoek…
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Alumni Masterclass: stress op de werkvloer
Alumni-activiteit
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Onderzoek
The aim of our research program is to better understand the aetiology and course of mood, anxiety and trauma and stressor-related disorders and to test and improve treatments for these disorders.
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Selectietoets BMAT
Op zaterdag 4 maart 2023 neem je deel aan de BMAT selectietoets. Deze vindt plaats in de Jaarbeurs (Beatrixgebouw) in Utrecht. In februari ontvang je een e-mail met praktische informatie over de BMAT.
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Selectietoets BMAT
Op zaterdag 4 maart 2023 neem je deel aan de BMAT selectietoets. Deze vindt plaats in de Jaarbeurs (Beatrixgebouw) in Utrecht. In februari ontvang je een e-mail met praktische informatie over de BMAT.
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Molecular pathways involved in renal injury-repair and ADPKD progression
Promotie
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Lectin complement activation pathway and the outcome of orthotopic liver transplantation
Promotie
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The role of the Bone Morphogenetic Protein Pathway in Colorectal Cancer
Promotie
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Onderzoek
Hoe verwerven mensen taal? Hoe kun je je brein trainen? Wat is het effect van stress op het brein van een ongeboren kind? LIBC-onderzoeksthema's variëren van psychiatrische stoornissen tot cognitieve robotica en van taalverwerking tot de impact van sociale factoren. Maak kennis met verschillende belangrijke…
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Studies on the Pathogenesis of Chronic Kidney Disease
In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…
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Targeting Chondrosarcoma and Osteosarcoma Cell metabolism -The IGF pathway and beyond
Promotie
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electrocatalytic CO2 reduction and concomitant catalyst degradation pathways
Promotie
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mRNA and drug delivery with lipid-based nanoparticles
This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.
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Optimally weighted ensembles of surrogate models for sequential parameter optimization
It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.
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Evolutionary Developmental Biology of Bitterling Fish
We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Lipid mediated colloidal interactions
The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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Calcas: Co-ordination Action for Innovation in Life-Cycle Analysis for Sustainability
Co-ordination Action for Innovation in Life-Cycle Analysis for Sustainability: deepening, broadening and leaping forward the LCA methodology.
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
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Functional brain responses in the maintenance of energy balance
Promotie
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Ocular responses to foreign corneal and tumor tissue
Promotie
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Modulation of the inflammatory response following myocardial infarction
Promotie
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Anti-glycan antibody responses during infection with Schistosoma
Promotie
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Genetic and methodological aspects of statin-induced lipid response
Promotie
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Monitoring the immune responses to vaccination and infection
Promotie
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Airway epithelial responses to rhinovirus, coronavirus and cigarette smoke
Promotie
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Meedoen aan onderzoek – Jeugd
De wetenschappers van het LUBEC doen onderzoek naar de effectiviteit van nieuwe behandelingen en trainingen. Uw kind kan deelnemen aan de onderstaande onderzoeksprojecten.
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PhD student Chronic effects of advanced materials on organisms(0.8-1.0 fte)
Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)
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Onderzoek Kind & Jeugd
De wetenschappers van het LUBEC doen onderzoek naar de effectiviteit van nieuwe behandelingen en trainingen. Uw kind of leerling kan deelnemen aan de volgende onderzoeksprojecten:
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Klinische Psychologie Lab
Psycho-physiologische reacties op stress.
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Reducing daily stress: Breaking a habit
Promotie
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Nanodeeltjes – redox eiwit biohybriden
Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…
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Nano shapes micro : Impacts of metallic nanoparticles on microbial communities
This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.
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Mentaal welzijn
Lees hoe je je geestelijk evenwicht bewaart.
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Stress op de werkvloer in tijden van Corona
Alumni-activiteit
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Self-regulation models
... which builds on self-regulation and stress-regulation theories and considers the modification of cognitions as a mediator of therapeutic change.
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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Computational modeling of mycobacterium infection and innate immune reponse in zebrafish
Promotor: Prof.dr. J.N. Kok
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Governance of Crises
De onderzoeksgroep ‘Governance of Crises’ bestudeert verschijnselen, dynamiek en spelers als het gaat om crisisbeheersing. Het Crisis Research Center (CRC) van de Universiteit Leiden maakt deel uit van deze onderzoekgroep.