Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.

Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

Animal Sciences’ contributions to the Host-Microbe Interactions research theme focus on the interaction of animal hosts with pathogenic microbes but also the beneficial role of the gut microbiome.

In Vietnam, foreign trade and culture are pervasive. Therefore, the need arises for students to learn more about cultural differences and intercultural communication. This dissertation focuses on improving training in intercultural communication in Vietnamese higher education.

Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

This study is the first to directly relate brain development to sex differences and school performance. The results debunk the myth that brain development is slower in boys.

Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.

In the theme Animal sciences and health research, we work with different species of animals to learn more about fundamental biological processes.

This part entails the analysis of an extensive sample of animal bone (c. 30,000 pieces) retrieved from well-defined archaeological contexts of the early period at Tell Sabi Abyad, c. 6800-6200 BC. It comprises aspects of taphonomy, ageing and osteometry, the reconstruction of the local spectrum of domestic…

We carry – and also feel – great responsibility for our laboratory animals. Animal welfare is very important to us. You can read below how we safeguard the welfare of our laboratory animals.

This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

The eighth issue of the JLGC explores the diverse and interdisciplinary research on our multifaceted relationship with animals which is currently taking place, re-examining the relationship between humans and animals, and the definitions involved.

Trust and reciprocity are two important social behaviors that help adolescents to navigate their social world successfully. In their empirical article in Journal of Research on Adolescence, van de Groep, Meuwese, Zanolie, Güroğlu, and Crone describe the development of trust and reciprocity in adolescents…

All biological and bio-medical research carried out at Leiden University is subject to strict conditions.

We only conduct research using laboratory animals if it is absolutely essential and we have no other means of answering the research question. Read here about how we assess and account for this research.

Kunst en vrije tijd, Kunst en vrije tijd

‘Visibility and secrecy are both valuable tactics and should not be antagonized in LGBT movements, ’ says Jingshu Zhu. Zhu defended her dissertation on Wednesday 21 February.

What does the interspecies interpretation of the equality principle mean for the liberal democracy, and is it possible to provide for an appropriate legal and political position for animals without defying the classic-liberal principles of the liberal democratic state?

My current research focuses on criminality and gender interactions in nineteenth-century Europe. This project uses a comparative methodology to explain gender constructions in a criminal and in a court setting.

Multiple Sclerosis, Parkinson’s and Alzheimer’s disease are the most common neurodegenerative disorders. Unfortunately, no effective treatments are currently available to halt the progression of these neuroinflammatory diseases [1].

This thesis aims at thinking through the ethical position of animals in a way that differs radically from the manner in which this ethical position is thought within contemporary animal rights discourse.

Cell adhesion signaling

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?

Regulating Relations: Controlling Sex and Marriage

The Animal Welfare Body is closely involved in all aspects of the research on laboratory animals.

Keeping and breeding of test animals for the purpose of scientific research and education.

Brendan Carroll promoted On Thursday October 30th Brendan Carroll successfully defended his PhD dissertation entitled:

Did early farmers deliberately use animal manure on their fields?

On 10 October 2019, Janneke Vink defended her thesis 'The Open Society and Its Animals'. The doctoral research was supervised by Prof. P.B. Cliteur.

Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…

Promotores: A.H. Meijer, H.P. Spaink

Can animal venoms yield novel antimicrobial peptides?

Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Does a snake die when it bites its lip? Why will a mongoose survive a scorpion’s sting, but we humans perish? These questions occupied the minds of toxin-enthusiasts and Master’s students Biology Jory van Thiel and Roel Wouters. They collected information from many sources and published their findings…

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Isotopic and zooarchaeological investigations in the Dominican Republic and Jamaica

Source: Mol Psychiatry (2015)

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

Mari Nakamura defended her thesis on 14 March 2017

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.