The long term goal of the Biophysical Organic Chemistry/SSNMR group, headed by Prof. Huub de Groot, is to reach an understanding of structure, dynamics and functional mechanisms of membrane proteins and self-organized biological assemblies and to translate this knowledge into new concepts for nano-devices,…

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Contact Biophysical Organic Chemistry/Solid State NMR

The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…

The two-year master’s programme Chemistry at Leiden Univerity offers a fundamental approach in finding tailored solutions for complex societal problems in human health and environmental issues. You can choose from four specialisations including Research in Chemistry and Chemistry an Business Studies…

Weekly Friday morning BPOC/SSNMR group meetings.

The Leiden Institute of Chemistry actively participates in several national research schools for MSc and PhD students. These schools are consortia that stimulate collaboration between research groups of the different participating Dutch universities. The research schools also offer advanced training…

The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR), Leids Instituut voor Chemisch Onderzoek (LIC)

Context-based learning has been implemented in secondary chemistry education. Hans Vogelzang, PhD at ICLON, reseached whether Scrum methodology might support creating context-based lessons. Scrum appears to be beneficial to learning outcomes. Defence on 10 November.

Peptides are routinely synthesized in the range of 5-80 amino acids, in an amount of 1-200 µmol (smaller and larger amounts are also possible).

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

The master’s specialisation Chemistry and Science Communication and Society at Leiden University bridges the gap between experts and the public by combining high quality research in chemistry with extensive training in science communication.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

Research training projects in the MCBIM group - Bachelor and master students of all chemistry related studies are more than welcome to take part in our research activities. We have various research projects, all in one way or another involving transition metal ions. Daily supervision in the laboratory…

We invite you to develop your academic skills by joining our research group and develop your own short term project in the bachelor phase. We offer longer term research projects for master students. 

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Demonstration experiments are a potentially powerful instrument to improve the micro-macro thinking of students in secondary education. Therefore we want to design a practical and generative approach to assist teachers to develop lessons with a demonstration experiment.

How can we understand the material instability of photographic (mixed media) artworks (1960s - present) from an integrated approach of Art History, Conservation Science and Chemistry in order to preserve these works for the future?

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…

Wiskunde en Natuurwetenschappen

Research at the BPOC/SSNMR group is comprised of the following research themes:

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

The master’s specialisation Chemistry and Education at Leiden University prepares students to teach the subject of chemistry to secondary school students. The programme comprises a one-year chemistry component, followed by an education component in the second year.

The main goal of the THEOR CHEM group, headed by Prof. Geert-Jan Kroes, is to achieve the ability to predict the outcome of chemical reactions involving hydrogen from first principles. This goal is important in almost all fields of chemistry and in many fields of physics.

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

The master’s specialisation Research in Chemistry at Leiden University offers research training founded on a profound theoretical basis. It prepares students who want to pursue a PhD degree in chemistry.

With Sylvestre Bonnet, Jeroen Codée and Remus Dame, the Leiden Institute of Chemistry (LIC) will be getting no less than three new professors. Bonnet will become professor in Bioinorganic Chemistry, Codée professor in Organic Chemistry and Dame professor in Molecular and Cellular Biochemistry.

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.

The mission in this research group, headed by Ad IJzerman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

Nathaniel Martin has been appointed professor in the field of Bioorganic Chemistry within the Faculty of Science at the Institute of Biology Leiden, starting from 1 March 2018. His research focuses on using new (bio)chemical approaches to combat infectious disease, as well as on developing new molecular…

Metabolomics group, LCQUI, Universidade UENF, Campos dos Goytacazes/Rio de Janeiro - Brazil

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

The master’s specialisation Chemistry and Business Studies at Leiden University bridges science and business development by focusing on areas such as technology management, innovation, entrepeneurship, operations, and decision making.

Dr. at the Department of organic chemistry, Wageningen University - the Nederlands

Lezing

The Plant BioDynamics Lab (PBDL) is a laboratory dedicated to experiments designed to develop and validate quantitative mathematical models of dynamical processes in biology. The principal objective of developing these models is to make quantitative predictions about these processes.

How are the building blocks of life formed?

As of July 1, Professor of Bio-organic Synthesis Hermen Overkleeft will be appointed as the Scientific Director of the Leiden Institute of Chemistry (LIC). He will succeed Jaap Brouwer, who has been managing the institute for the past twelve years. Overkleeft has been appointed for a period of four…

The Supramolecular & Biomaterials Chemistry group of Prof. dr. Alexander Kros is active in the field of self-assembly of amphiphilic peptides and applying them in supramolecular chemistry.

Promotor: G.R. de Snoo