Promotor: T.H. Oosterkamp

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

Binnen het Graduate Programme van Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) is de aanvraag voor de 'Netherlands Magnetic Resonance Research School' gehonoreerd. Deze onderzoeksschool is een van de 18 gehonoreerde aanvragen. Vier Leidse Graduate Schools zijn gehonoreerd.

Promotor: Prof.dr. M. Ubbink

Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: M. Haverkorn

Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

Promotor: H.J.M. de Groot

Huub de Groot

Promotor: S.M. Verduyn Lunel

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Wiskunde en Natuurwetenschappen

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A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Leidse onderzoekers hebben minuscule bewegingen gevonden in het laccase-enzym. Deze ontdekking kan leiden tot de ontwikkeling van veel efficiëntere biobrandstofcellen. Publicatie in Biophysical Journal.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

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The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Speciale versterkstoffen kunnen MRI-scanners honderden malen gevoeliger maken. Leidse fysici hebben nu een methode gevonden om hun efficiëntie te toetsen. Gevoeligere MRI-scans kunnen bijvoorbeeld taaislijmziekte of Parkinson begrijpelijker maken. Publicatie op 18 januari in PCCP.

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Een nieuwe NMR-microscoop geeft natuurkundigen een verbeterd instrument om fundamentele fysische processen te onderzoeken. Het biedt ook nieuwe mogelijkheden voor de medische wetenschap, bijvoorbeeld om eiwitten beter te bestuderen in de hersenen van Alzheimerpatiënten. Publicatie in Physical Review…

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This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

De nieuwe Leidse paramagnetische Nuclear Magnetic Resonance (paraNMR)-faciliteit wordt op woensdag 11 september officieel geopend. De faciliteit biedt externe gebruikers, zowel nationaal als internationaal, expertise op het zeer geavanceerde terrein van paraNMR-onderzoek.

Op vrijdag 25 mei is de oratie van Tjerk Oosterkamp over zijn leeropdracht 'Experimentele Natuurkunde'.

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

Fotosynthese is de oorsprong van het leven op aarde, maar ook nog grotendeels onbegrepen. Neem bijvoorbeeld het geweldig efficiënte mechanisme van het elektronentransport. Leidse onderzoekers laten voor het eerst zien waar een oorzaak hiervan te vinden is.