Promotor: T.H. Oosterkamp

A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Control of Living Cells by Magnetic Fluorescent Nanoparticles

X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.

Our cantilevers have a low intrinsic damping rate: this enables us to measure with low noise, since damping is proportionate to noise. However, when the magnet is close to the surface of a sample we want to study, we measure a much higher effective damping rate. This is caused by magnetic interaction…

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: Dr. M. Haverkorn

Promotor: Prof.dr. M. Ubbink

Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

Political scientists Huib Pellikaan and Niels van Willigen (Leiden University) use and elaborate on the theoretical insights from game theory in order to understand nuclear security in changing environment. Now that the relations between the US and Russia have deteriorated and smaller nuclear states…

Political scientist Nicolas Blarel (Leiden University) analsyses how non-state actors can (directly or directly) attempt to provoke conditions for a crisis between state actors that have nuclear capabilities. He argues that there is an urgent but complicated and understudied task to understand and manage…

Promotor: Prof.dr.ir. J.W.M. Hilgenkamp, Prof.dr. J. van den Brink

First author Rubin Dasgupta, PhD student at the Biophysical Organic Chemistry & Macromolecular Biochemistry groups at the Leiden Institute of Chemistry has made the cover of the June edition of Solid State Nuclear Magnetic Resonance.

Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.

How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?

We explore the possibilities to combine magnetic resonance techniques with atomic force microscopy together in a single microscope: the MRI-AFM, also called Magnetic Resonance Force Microscopy (MRFM).

A deceptively simple, complicated paper

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

In my group (the Aarts lab) we combine or structure materials, mostly in thin film form, in such a way that the hybrid has different and novel properties or functionalities.

Can metabolomic profiling be used to predict resistance against insect herbivores in plants?

PURPOSE: To determine the effect of elasticity on the skin permeation of ketoprofen from surfactant-based vesicular formulations and elastic liposomes.

Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…

How does contemporary art and culture represent nuclear contamination in post-nuclear landscapes?

You can still enroll for the master Magnetic Resonance Physics course. It starts at Monday, Nov. 13th 13:30 in HL 226. For more information go to https://studiegids.leidenuniv.nl/courses/show/76629/magnetic-resonance-physics

Can a proposed new radiofrequency approach to graphene biosensors lead to groundbreaking changes in genome mapping?

In this thesis, I studied the origin and evolution of the non-thermal radiation in merging galaxy clusters.

The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.

Over time Dutch and Indonesian composers, performers and music scholars have inspired each other and they continue to do so. The presence of the Dutch in the Netherlands East-Indies and Indonesia, but also the existence of large diasporic communities in the Netherlands have contributed to a mutual exchange…

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.